Courses

Advanced Analysis of Qualitative Data
COD Workload Description
313A8-02 30 This course addresses: Approaches, methods and techniques for qualitative research in Psychology; The main theoretical-methodological currents that support qualitative analyses in human sciences investigations; Research methods and procedures for the collection and analysis of different types of research employing the qualitative method.
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
CTBMF Master's Not required
CTBMF Doctorate Not required
Clinical Psychology Master's Not required
Clinical Psychology Doctorate Required
Clinical Stomatology Master's Not required
Clinical Stomatology Doctorate Not required
Dental Materials Master's Not required
Dental Materials Doctorate Not required
Dental Prosthetics Master's Not required
Dental Prosthetics Doctorate Not required
Education Master's Not required
Education Doctorate Not required
Endodontics Master's Not required
Endodontics Doctorate Not required
Ethics and Political Philosophy Master's Not required
Ethics and Political Philosophy Doctorate Not required
Human Cognition Master's Not required
Human Cognition Doctorate Required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Metaphysics and Epistemology Master's Not required
Metaphysics and Epistemology Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Orthodontics and Facial Orthopedics Master's Not required
Orthodontics and Facial Orthopedics Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Psychology Master's Not required
Psychology Doctorate Not required
Restorative Dentistry Master's Not required
Restorative Dentistry Doctorate Not required
Social Psychology Master's Not required
Social Psychology Doctorate Required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Education theories and cultures Seeks to explore the relationship between anthropology, history, philosophy, sociology and education, by discussing political and cultural conditions in education. It brings together theoretical and empirical theories and research, so improving our understanding of the diversity of the human experience in the different processes of development.
People and education It studies education as a process that involves the person's non-development, training and self-training, highlighting its intertwining as health and well-being. It hosts interdisciplinary studies and research that enhance the pedagogical dimension of human experience in its interactions as biological, psychosocial, biographical, cultural aspects of two subjects and subjectivities in contemporary society.
Education in Science and Mathematics (ESM) Studies teaching and learning in Science and Mathematics in different training spaces, using theoretical and methodological contributions related to education through research; epistemologically linked to the domain of language, to inter and transdisciplinarity – to science and the nature of being and to the modeling processes in Science and Mathematics, associated with initial and continuing teacher training, in Basic Education and Higher Education. It covers research involving scientific and technological development, scientific literacy and the popularization of Science and Mathematics in formal and non-formal spaces of education.
Education training, policies and practices Seeks to explore educational processes in different training settings, from socio-political, historical and cultural perspectives, aiming at a critical analysis of policies, training practices, and educational planning in different contexts. It scrutinizes pedagogical practices in several degrees and types of education, enabling insights for decision making regarding changes in society and in the educational process.
The State and Theories of Justice This line of research addresses the theoretical and pragmatic aspects of the theories of justice from scholars such as Immanuel Kant, John Rawls and Jürgen Habermas, as well as their different critical and alternative views in communitarian and utilitarian theories.
Ethics Principles This line of research addresses the central issues of Ethics as they have been conceived over time and under the systematic aspect, in view of scholars such as Plato, Aristotle, Kant and others. The relationship between practical and theoretical reason is a central area.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Phenomenology and Hermeneutics This line of research is intended to analyze the classical theories of knowledge under the perspective of the philosophers of phenomenology, which has been the norm in Europe for almost a century and has representatives all over the world.
Philosophy in the Middle Ages This line of research addresses philosophers of the Middle Ages.
Analytic Epistemology This line of research addresses the fundamental topics of contemporary Epistemology: theories of knowledge, theories of epistemic rationality, skepticism and epistemic paradoxes.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Well-being, health and quality of life This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains.
Assessment and psychological interventions in mental health This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus.
Psychosocial Processes: Practices and contexts This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge.
Cognition, brain and behavior This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Advanced Biomechanics
COD Workload Description
1937N-03 45 Study of the kinetic, kinematic, and electrophysiological aspects of human movement applied to research. Study of in vivo muscle architecture and muscle mechanical properties. Analysis of surface electromyography. Study of research techniques in biomechanics, kinetics, kinematics, and electromyography, through a theoretical-practical approach in the laboratory.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Aging and Mental Health
COD Workload Description
10557-02 30 The course aims to study normal and pathological aging, focusing on the main mental illnesses within this age group. By studying these disorders, it highlights the epidemiological condition, the clinical picture, the main and differential diagnosis of pathologies and treatment for them. Additionally, it provides deeper insights into the understanding of the relationship between health professionals, caregivers and geriatric patients.
Professors Home time Lattes
ALFREDO CATALDO NETO 33 years and 3 months Link
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Aging and Neuropsychology of Cognitive Functions
COD Workload Description
40502-02 30 This course addresses the influence of aging on an individual's cognitive functions. We know that aging brings about disorders and losses at both the cognitive and behavioral levels, and these disorders are part of a healthy aging process. However, some cognitive abilities are more severely affected than expected, which may indicate a risk for the development of a neurodegenerative disease.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Aging and Physical Activity
COD Workload Description
20598-02 30 The course will address the different dimensions of aging and their relationship with a physically active lifestyle. By addressing a myriad of benefits for the health of elderly people who are either healthy or suffering from non-communicable diseases, it will focus on studies and discussions on improving quality of life and mortality reduction.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Aging and neurobiology of motor control
COD Workload Description
1931A-02 30 This course introduces the main concepts and theories associated with the neurobiology of motor control, emphasizing the sensory-cognitive-motor changes during the aging process. Moreover, the motor control in prevalent diseases and dysfunctions such as stroke, Parkinson's and Alzheimer's disease are also studied. Hence, the following points will be addressed: Theories and models of motor control; Evolution of motor systems; Cortical, subcortical and spinal cord circuits of movement; Selection of motor patterns; Neural networks for the generation of rhythmic motor behaviors; Sensory feedback in the control of posture and locomotion; Coordination of rhythmic movements; Reach and grasp movements; Plasticity and learning in motor control networks; Multimodal integrations of the central nervous system and motor control.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Cellular and Molecular Biology Master's Not required
Cellular and Molecular Biology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Assessment Methodology in Research
COD Workload Description
63339-02 30 Understanding the basic concepts of biostatistics is basicl for the planning, collection, evaluation and interpretation of data obtained in health research. Thus, this course aims to equip students to describe and perform basic analysis and present research data.
Professors Home time Lattes
THIAGO WENDT VIOLA 4 years and 4 months Link
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Pediatrics Master's Required
Pediatrics Inter-institutional doctorate degree Required
Pediatrics Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
BIOETHICS IN DENTISTRY
COD Workload Description
83274-02 30 The objective of this course is to provide a systematic study of relevant themes or issues, as well as the ethical dilemmas that emerge from the theoretical and practical field of Biomedical Sciences.
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biology and Orofacial Rehabilitation Master's Not required
Biology and Orofacial Rehabilitation Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
CTBMF Master's Not required
CTBMF Doctorate Not required
Clinical Stomatology Master's Not required
Clinical Stomatology Doctorate Not required
Dental Materials Master's Not required
Dental Materials Doctorate Not required
Dental Prosthetics Master's Not required
Dental Prosthetics Doctorate Not required
Endodontics Master's Not required
Endodontics Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Ontological Clinic Master's Not required
Ontological Clinic Doctorate Not required
Orthodontics and Facial Orthopedics Master's Not required
Orthodontics and Facial Orthopedics Doctorate Not required
Restorative Dentistry Master's Not required
Restorative Dentistry Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
oral biology Master's Not required
oral biology Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Etiopathogenesis and Treatment of Periodontal and Periapical Diseases This line of research aims to study the mechanisms involved in periapical and periodontal alterations, aiming to analyze their relationship with systemic diseases, as well as to identify new treatment strategies for these conditions.
Etiopathogenesis and Treatment in Stomatology The objectives of this line of research involve the evaluation of the pathophysiology of diseases affecting the oral mucosa and salivary glands, including oral cancer, focusing on the clinical, immunological, and pathological aspects of these conditions, in order to identify new forms of prevention and treatment of such diseases.
Pediatric Oral Health This line of research aims to evaluate new approaches to the prevention, diagnosis, and treatment of oral cavity disorders, focusing on the management of pediatric patients.
Restorative and Reconstructive Dentistry This line of research focuses on developing new technologies and approaches aimed at aesthetic and functional oral rehabilitation, using laboratory and clinical assessment methodologies. It also includes new approaches for the orthodontic, orthopedic, and surgical correction of orofacial deformities, seeking to improve the diagnosis and management of patients with these conditions.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Biomechanics, Pain and Orofacial Dysfunction This line of research is aimed to analyze the pathophysiology of orofacial pain, temporomandibular dysfunction, bruxism and parafunctional habits, focusing on the biomechanical characterization of the stomatognathic system and its reflexes on the organism, seeking to identify new diagnostic and therapeutic strategies for these conditions.
Biomaterials and Tissue Engineering This line of research aims at the development and evaluation of the efficacy and safety of new dental materials, as well as innovative tissue engineering strategies, focusing on tissue regeneration and the reduction of infectious oral complications.
Microbiology and Oral Immunology This line of research aims to develop research with a specific focus on oral microbiology and oral immunology, for diagnostic and therapeutic purposes.
Bioethics in Gerontology
COD Workload Description
10528-02 30 The topics that will be addressed in this course are: study of existing relationship between Ethics, Morality and Law; Bioethics as Applied Ethics; a comparison between different explanatory models used in Bioethics; a reflection on the ethical aspects involved in issues relating to privacy and confidentiality, end of life issues, allocation of scarce resources, respect for persons and decision-making, elder abuse, and research on the elderly.
Professors Home time Lattes
JOSE ROBERTO GOLDIM 24 years and 4 months Link
Concentration area Type Required
Biomedical Gerontology Master's Required
Biomedical Gerontology Doctorate Required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Biology of Aging
COD Workload Description
40504-04 60 The topics that will be addressed in this course are: Study of biological phenomena involved in the aging process of living beings; An analysis of the different theories intended to explain aging and the endogenous and exogenous factors affecting this process; Mechanisms for replicative senescence: stochastic mechanisms, signal transduction and regulation of cell proliferation, genetic mechanisms; Experimental models for the study of aging; Genetic factors involved in the process of senescence; Cellular and molecular mechanisms of immunosenescence; Immunological risk; Premature immune aging; Modulation of immunosenescence.
Professors Home time Lattes
MOISES EVANDRO BAUER 24 years and 11 months Link
DENISE CANTARELLI MACHADO 26 years and 11 months Link
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Required
Biomedical Gerontology Doctorate Required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Biomechanics and motor control in older adults
COD Workload Description
193BA-03 45 Study of the biomechanics and neurobiology of motor control in older adults, thus addressing human locomotion/gait, muscle architecture and its mechanical properties, and the analysis of surface electromyography. The main concepts and theories regarding the processes of motor behavior in the aging process are also discussed, including common changes occurring in stroke, Parkinson's, and Alzheimer's diseases. Learning through research techniques and theoretical-practical laboratory activities will be used to address the subject topics, from biomechanical aspects to central nervous system control and integration.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Biomechanics of aging
COD Workload Description
1933K-04 60 Study of the kinetic, kinematic and electrophysiological aspects of human gait applied to the health of the elderly. Study of in vivo muscle architecture and muscle mechanical properties during aging. Analysis of surface electromyography in the elderly. Study of research techniques in biomechanics, kinetics, kinematics and electromyography, through a theoretical-practical approach in the laboratory, applied to aging.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Biomedical Image Processing and Analysis
COD Workload Description
1935M-03 45 Fundamentals of the acquisition and storage processes of digital biomedical images. Presentation of pre-processing methods for enhancement, noise reduction, and corrections. Study of the fundamentals of filtering in the spatial and frequency domain and their applications. Development of segmentation techniques applied to gray-scale and multispectral biomedical images. Quantitative analysis of biomedical images and pattern recognition methods. Discussion of biomedical research using digital image processing and analysis.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Biomedical Research Methodology: Quantitative Methods
COD Workload Description
20533-03 45 This course seeks to get students acquainted to the various available instruments which can be used in a quantitative approach to epidemiological research. A quantitative analysis is an analysis of data from a research tool in which data with predefined numeric or categorical values had been collected. Students will make use of the following software: EpiInfo, SPSS and EXCEL. EpiInfo is open source software designed to be used by the researcher in every stage, from data tabulation to data preparation and analysis, thus generating various kinds of charts.
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Cellular and Molecular Biology Master's Not required
Cellular and Molecular Biology Doctorate Not required
Clinical Psychology Master's Not required
Clinical Psychology Doctorate Not required
Human Cognition Master's Not required
Human Cognition Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Psychology Doctorate Not required
Social Psychology Master's Not required
Social Psychology Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Assessment and psychological interventions in mental health This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus.
Psychosocial Processes: Practices and contexts This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge.
Cognition, brain and behavior This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience.
Well-being, health and quality of life This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Cardiometabolism and aging
COD Workload Description
193BB-02 30 In the course, the most prevalent cardiometabolic diseases associated with aging will be addressed, with a basis on diagnosis and management (pharmacological and non-pharmacological), aiming to stimulate promotion and prevention measures, in an interdisciplinary perspective.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
DENTAL BIOSTATISTICS
COD Workload Description
83293-02 30 The purpose of this course is to introduce the essential aspects of statistics and their applications in dental research. It will promote the understanding of the elements of statistical inference and to help identify and choose the main basic statistical procedures that occur in practice. It will also present the justification for the calculation of sample size in different dental research situations.
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biology and Orofacial Rehabilitation Master's Not required
Biology and Orofacial Rehabilitation Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
CTBMF Master's Not required
CTBMF Doctorate Not required
Cellular and Molecular Biology Master's Not required
Cellular and Molecular Biology Doctorate Not required
Clinical Psychology Master's Not required
Clinical Psychology Doctorate Not required
Clinical Stomatology Master's Not required
Clinical Stomatology Doctorate Not required
Dental Materials Master's Not required
Dental Materials Doctorate Not required
Dental Prosthetics Master's Not required
Dental Prosthetics Doctorate Not required
Endodontics Master's Not required
Endodontics Doctorate Not required
Human Cognition Master's Not required
Human Cognition Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Ontological Clinic Master's Not required
Ontological Clinic Doctorate Not required
Orthodontics and Facial Orthopedics Master's Not required
Orthodontics and Facial Orthopedics Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Psychology Doctorate Not required
Restorative Dentistry Master's Not required
Restorative Dentistry Doctorate Not required
Social Psychology Master's Not required
Social Psychology Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
oral biology Master's Not required
oral biology Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Etiopathogenesis and Treatment of Periodontal and Periapical Diseases This line of research aims to study the mechanisms involved in periapical and periodontal alterations, aiming to analyze their relationship with systemic diseases, as well as to identify new treatment strategies for these conditions.
Etiopathogenesis and Treatment in Stomatology The objectives of this line of research involve the evaluation of the pathophysiology of diseases affecting the oral mucosa and salivary glands, including oral cancer, focusing on the clinical, immunological, and pathological aspects of these conditions, in order to identify new forms of prevention and treatment of such diseases.
Pediatric Oral Health This line of research aims to evaluate new approaches to the prevention, diagnosis, and treatment of oral cavity disorders, focusing on the management of pediatric patients.
Restorative and Reconstructive Dentistry This line of research focuses on developing new technologies and approaches aimed at aesthetic and functional oral rehabilitation, using laboratory and clinical assessment methodologies. It also includes new approaches for the orthodontic, orthopedic, and surgical correction of orofacial deformities, seeking to improve the diagnosis and management of patients with these conditions.
Assessment and psychological interventions in mental health This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus.
Psychosocial Processes: Practices and contexts This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge.
Cognition, brain and behavior This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience.
Well-being, health and quality of life This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Biomechanics, Pain and Orofacial Dysfunction This line of research is aimed to analyze the pathophysiology of orofacial pain, temporomandibular dysfunction, bruxism and parafunctional habits, focusing on the biomechanical characterization of the stomatognathic system and its reflexes on the organism, seeking to identify new diagnostic and therapeutic strategies for these conditions.
Biomaterials and Tissue Engineering This line of research aims at the development and evaluation of the efficacy and safety of new dental materials, as well as innovative tissue engineering strategies, focusing on tissue regeneration and the reduction of infectious oral complications.
Microbiology and Oral Immunology This line of research aims to develop research with a specific focus on oral microbiology and oral immunology, for diagnostic and therapeutic purposes.
DENTAL EPIDEMIOLOGY
COD Workload Description
83292-02 30 This course covers the basic principles of epidemiology, identifying the biosocial indicators of the health-disease processes of cavities and periodontal disease, seeking to identify the existing connections related to them. The specific objectives are:
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biology and Orofacial Rehabilitation Master's Not required
Biology and Orofacial Rehabilitation Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
CTBMF Master's Not required
CTBMF Doctorate Not required
Clinical Stomatology Master's Not required
Clinical Stomatology Doctorate Not required
Dental Materials Master's Not required
Dental Materials Doctorate Not required
Dental Prosthetics Master's Not required
Dental Prosthetics Doctorate Not required
Endodontics Master's Not required
Endodontics Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Ontological Clinic Master's Not required
Ontological Clinic Doctorate Not required
Orthodontics and Facial Orthopedics Master's Not required
Orthodontics and Facial Orthopedics Doctorate Not required
Restorative Dentistry Master's Not required
Restorative Dentistry Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
oral biology Master's Not required
oral biology Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Etiopathogenesis and Treatment of Periodontal and Periapical Diseases This line of research aims to study the mechanisms involved in periapical and periodontal alterations, aiming to analyze their relationship with systemic diseases, as well as to identify new treatment strategies for these conditions.
Etiopathogenesis and Treatment in Stomatology The objectives of this line of research involve the evaluation of the pathophysiology of diseases affecting the oral mucosa and salivary glands, including oral cancer, focusing on the clinical, immunological, and pathological aspects of these conditions, in order to identify new forms of prevention and treatment of such diseases.
Pediatric Oral Health This line of research aims to evaluate new approaches to the prevention, diagnosis, and treatment of oral cavity disorders, focusing on the management of pediatric patients.
Restorative and Reconstructive Dentistry This line of research focuses on developing new technologies and approaches aimed at aesthetic and functional oral rehabilitation, using laboratory and clinical assessment methodologies. It also includes new approaches for the orthodontic, orthopedic, and surgical correction of orofacial deformities, seeking to improve the diagnosis and management of patients with these conditions.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Biomechanics, Pain and Orofacial Dysfunction This line of research is aimed to analyze the pathophysiology of orofacial pain, temporomandibular dysfunction, bruxism and parafunctional habits, focusing on the biomechanical characterization of the stomatognathic system and its reflexes on the organism, seeking to identify new diagnostic and therapeutic strategies for these conditions.
Biomaterials and Tissue Engineering This line of research aims at the development and evaluation of the efficacy and safety of new dental materials, as well as innovative tissue engineering strategies, focusing on tissue regeneration and the reduction of infectious oral complications.
Microbiology and Oral Immunology This line of research aims to develop research with a specific focus on oral microbiology and oral immunology, for diagnostic and therapeutic purposes.
Development and Elaboration of Research Projects
COD Workload Description
63341-04 60 The elaboration of a high-quality project is essential for the progress of scientific research. Thus, this course aims to qualify equip students to write and present a project in both clinical and experimental areas by discussing basic concepts of the anatomy and physiology of a research project.
Professors Home time Lattes
RENATO TETELBOM STEIN 38 years and 4 months Link
FREDERICO ORLANDO FRIEDRICH 1 year and 10 months Link
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
CTBMF Master's Not required
CTBMF Doctorate Not required
Clinical Psychology Master's Not required
Clinical Psychology Doctorate Not required
Clinical Stomatology Master's Not required
Clinical Stomatology Doctorate Not required
Dental Materials Master's Not required
Dental Materials Doctorate Not required
Dental Prosthetics Master's Not required
Dental Prosthetics Doctorate Not required
Endodontics Master's Not required
Endodontics Doctorate Not required
Human Cognition Master's Not required
Human Cognition Doctorate Not required
Orthodontics and Facial Orthopedics Master's Not required
Orthodontics and Facial Orthopedics Doctorate Not required
Pediatrics Master's Required
Pediatrics Inter-institutional doctorate degree Required
Pediatrics Doctorate Not required
Psychology Doctorate Not required
Restorative Dentistry Master's Not required
Restorative Dentistry Doctorate Not required
Social Psychology Master's Not required
Social Psychology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Assessment and psychological interventions in mental health This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus.
Psychosocial Processes: Practices and contexts This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge.
Cognition, brain and behavior This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience.
Well-being, health and quality of life This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains.
ETHICS IN DENTISTRY
COD Workload Description
83278-02 30 To identify the nature of the epidemiological study; to describe different epidemiological methods; to name and characterize the indexes of epidemiological nature related to cavities and periodontal disease; to establish the main interrelations between biological and social indicators with the development of cavities and periodontal disease; to organize epidemiological surveys; to apply epidemiological indices of cavities and periodontal disease; to analyze and interpret the results of epidemiological studies.The course brings the fundamental concepts of Ethics in order to achieve the following goals: the formulation of correct ethical judgments; proper use of ethical principles in individual, family, professional, social and political daily life; understanding and developing the ability to criticize, accept or refuse principles of action in the various aspects of daily life; understanding and searching for solutions to some of the serious problems that defy humanity through applied Ethics.
Professors Home time Lattes
JOAO BATISTA BLESSMANN WEBER 30 years and 11 months Link
Concentration area Type Required
Biology and Orofacial Rehabilitation Master's Not required
Biology and Orofacial Rehabilitation Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
CTBMF Master's Not required
CTBMF Doctorate Not required
Clinical Psychology Master's Not required
Clinical Psychology Doctorate Not required
Clinical Stomatology Master's Not required
Clinical Stomatology Doctorate Not required
Dental Materials Master's Not required
Dental Materials Doctorate Not required
Dental Prosthetics Master's Not required
Dental Prosthetics Doctorate Not required
Endodontics Master's Not required
Endodontics Doctorate Not required
Human Cognition Master's Not required
Human Cognition Doctorate Not required
Ontological Clinic Master's Not required
Ontological Clinic Doctorate Not required
Orthodontics and Facial Orthopedics Master's Not required
Orthodontics and Facial Orthopedics Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Psychology Doctorate Not required
Restorative Dentistry Master's Not required
Restorative Dentistry Doctorate Not required
Social Psychology Master's Not required
Social Psychology Doctorate Not required
oral biology Master's Not required
oral biology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Etiopathogenesis and Treatment of Periodontal and Periapical Diseases This line of research aims to study the mechanisms involved in periapical and periodontal alterations, aiming to analyze their relationship with systemic diseases, as well as to identify new treatment strategies for these conditions.
Etiopathogenesis and Treatment in Stomatology The objectives of this line of research involve the evaluation of the pathophysiology of diseases affecting the oral mucosa and salivary glands, including oral cancer, focusing on the clinical, immunological, and pathological aspects of these conditions, in order to identify new forms of prevention and treatment of such diseases.
Pediatric Oral Health This line of research aims to evaluate new approaches to the prevention, diagnosis, and treatment of oral cavity disorders, focusing on the management of pediatric patients.
Restorative and Reconstructive Dentistry This line of research focuses on developing new technologies and approaches aimed at aesthetic and functional oral rehabilitation, using laboratory and clinical assessment methodologies. It also includes new approaches for the orthodontic, orthopedic, and surgical correction of orofacial deformities, seeking to improve the diagnosis and management of patients with these conditions.
Assessment and psychological interventions in mental health This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus.
Psychosocial Processes: Practices and contexts This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge.
Cognition, brain and behavior This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience.
Well-being, health and quality of life This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains.
Biomechanics, Pain and Orofacial Dysfunction This line of research is aimed to analyze the pathophysiology of orofacial pain, temporomandibular dysfunction, bruxism and parafunctional habits, focusing on the biomechanical characterization of the stomatognathic system and its reflexes on the organism, seeking to identify new diagnostic and therapeutic strategies for these conditions.
Biomaterials and Tissue Engineering This line of research aims at the development and evaluation of the efficacy and safety of new dental materials, as well as innovative tissue engineering strategies, focusing on tissue regeneration and the reduction of infectious oral complications.
Microbiology and Oral Immunology This line of research aims to develop research with a specific focus on oral microbiology and oral immunology, for diagnostic and therapeutic purposes.
Elderly Patient Safety
COD Workload Description
1932D-02 30 The course addresses aging and elderly patient safety based on the recommendations of the World Health Organization, the World Alliance for Patient Safety and the National Patient Safety Program, from the perspective of a look and instrumentalization for safe and effective practices. for the involvement of the elderly and their families.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
English article writing
COD Workload Description
1932B-02 30 Scientific development is a continuous and systematic process of actions aimed at contributing to academic excellence, based on teaching and research. The production of knowledge alone is not enough to consolidate the qualification of graduate students. Dissemination of knowledge is required for the scientific community and society as a whole. The dissemination of new knowledge acquired at our University and the sharing of knowledge globally can only be intensified when they are disseminated in a common peer language, facilitating interaction between teaching and research institutions from different countries. Today, internationalization is mandatory for continued development and scientific recognition. To this end, our graduate students will be required to receive English language training in the dissemination of their productions to the scientific community in international journals, as expected for the excellent graduate programs.
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Epidemiological Method Practice
COD Workload Description
20500-02 30 The course aims at fostering a critical reflection on the scientific method and its practical use in research. It will address, in a practical way, the concepts of clinical epidemiology and biostatistics by means of their application in research projects developed by graduate students. It will enable the discussion of all elements of a research project, with emphasis on the methods used by each student in their research project.
Professors Home time Lattes
CARLA HELENA AUGUSTIN SCHWANKE 22 years and 4 months Link
REGIS GEMERASCA MESTRINER 13 years and 4 months Link
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Epidemiology in Health
COD Workload Description
63340-02 30 Clinical epidemiology is a basic tool for evidence-based clinical medicine. This course studies clinical events in a specific group of people, using standardized scientific methods, with the purpose of producing accurate and valid information, for a better treatment and prevention of diseases.
Professors Home time Lattes
FREDERICO ORLANDO FRIEDRICH 1 year and 10 months Link
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Pediatrics Master's Required
Pediatrics Inter-institutional doctorate degree Required
Pediatrics Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Evolutionary and molecular evidence of human aging
COD Workload Description
1933L-02 30 In-depth investigation of the genetic and molecular mechanisms of human aging. Studies related to the differences in the processes of survival and collapse after the reproductive period that occurs between humans and other mammals. Search for possible answers to the question: “why do we age?”.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Fundamentals of Medical Imaging Technologies: An Interdisciplinary Approach
COD Workload Description
1932C-03 45 The course will provide a comprehensive overview of the most relevant diagnostic imaging modalities used in radiology and nuclear medicine, covering both clinical and technical aspects, throughout an interdisciplinary approach. The course will introduce the physical principles underlying different medical imaging modalities along with examples of specific applications. The basic principles of digital image processing, including common terminology and the components that define image quality will be discussed. The ongoing research and new developments in molecular and hybrid imaging modalities will be discussed.
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Gerontological Demography and Epidemiology
COD Workload Description
10586-02 30 The course addresses the basic concepts of Demography and Epidemiology, as well as Biostatistics, and consist of lectures and seminars delivered by graduate students to their classmates after research and preparation. It allows the discussion on the themes presented by each student, as professors will play the role of a mediator, who will also complement the topics stated in the syllabus, when applicable. The idea is to encourage critical thinking on population aging and the scientific method used in demographic analyses, clinical and epidemiological research.
Professors Home time Lattes
ANGELO JOSE GONCALVES BOS 26 years and 10 months Link
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Health Care in the Process of Health-Disease in the Elderly
COD Workload Description
20537-03 45 Contents related to the study of health care in the health-disease process among the elderly will be studied, including an holistic and interdisciplinary view of aging. Additionally, national and international policies for the elderly, terminality, and the role of caregivers will be discussed.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Health, Disease and Prevention in Old Age
COD Workload Description
193BL-03 45 The discipline focuses on the study of care in the health-disease process in the elderly, including a holistic view of aging and interdisciplinarity, including national and international policies related to the elderly, terminality and the role of caregivers. Additionally, Geriatric Prevention, its principles, objectives, techniques and methods will be addressed. Determining factors of longevity and their relationship with biological aging and prevalent diseases. Importance of social rehabilitation of the elderly and their quality of life.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Innovation and Entrepreneurship in Health and Human Aging
COD Workload Description
1937M-02 30 Study of innovation ecosystems. Analysis of the components and organization of innovation and entrepreneurship environments, applied to the health of the elderly. Study on university, business, and government cooperation. Reflections on the relationship between innovation, science, and technology, especially regarding healthy aging. Study on Health Competence and Excellence Centers. Analysis of Incubators and the promotion of entrepreneurship in elderly health. Discussions on Technological Parks and Technological Innovation Centers.
Professors Home time Lattes
RAFAEL REIMANN BAPTISTA 16 years and 4 months Link
DANIEL RODRIGO MARINOWIC 5 years and 4 months Link
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Integrity and Ethics on Research
COD Workload Description
19302-02 30 Nowadays, with the free access to knowledge and data through social networks and the Internet, the number of cases of misconduct in research execution and publication around the world is increasing, leading to the loss of the credibility of scientific publications. This course aims to guide students about good research practices, from the projects execution to the results communication and publication, stressing the importance of research data adequate registration.
Professors Home time Lattes
DENISE CANTARELLI MACHADO 26 years and 11 months Link
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Required
Biochemical and Molecular Pharmacology Doctorate Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
CTBMF Master's Not required
CTBMF Doctorate Not required
Clinical Psychology Master's Not required
Clinical Psychology Doctorate Not required
Clinical Stomatology Master's Not required
Clinical Stomatology Doctorate Not required
Dental Materials Master's Not required
Dental Materials Doctorate Not required
Dental Prosthetics Master's Not required
Dental Prosthetics Doctorate Not required
Endodontics Master's Not required
Endodontics Doctorate Not required
Human Cognition Master's Not required
Human Cognition Doctorate Not required
Medical Practice Master's Required
Medical Practice Doctorate Required
Nephrology Master's Required
Nephrology Doctorate Required
Neurosciences Master's Required
Neurosciences Doctorate Required
Orthodontics and Facial Orthopedics Master's Not required
Orthodontics and Facial Orthopedics Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Psychology Doctorate Not required
Restorative Dentistry Master's Not required
Restorative Dentistry Doctorate Not required
Social Psychology Master's Not required
Social Psychology Doctorate Not required
Surgical Practice Master's Required
Surgical Practice Doctorate Required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Assessment and psychological interventions in mental health This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus.
Psychosocial Processes: Practices and contexts This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge.
Cognition, brain and behavior This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience.
Well-being, health and quality of life This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Interdisciplinary Gerontology Seminars I
COD Workload Description
20535-02 30 The Interdisciplinary Gerontology Seminars I are intended to provide a consistent follow-up to topics that deal with aging under the scope of interdisciplinarity, thus fostering a critical reflection on the meaning of aging and its biological, psychological, social, economic and cultural consequences. It is also intended to present scenarios related to research and publication.
Professors Home time Lattes
CRISTINA MARIA MORIGUCHI JECKEL 22 years and 3 months Link
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Interdisciplinary Gerontology Seminars II
COD Workload Description
20536-02 30 The topics that will be addressed in this course are: Humanism and/or technology in education; Advisor's and professor's responsibility and their relationship with students, thus forming a basic model of teaching/learning/research/publication; Fundamental characteristics, potentialities and abilities for professors and students; Teaching, learning and classroom dynamics; Professors/advisors as models to be followed.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Introduction to Geriatrics and Gerontology
COD Workload Description
20532-03 45 With the population aging, there is also an increase in morbidity among the elderly. Thus, it is paramount to study the clinical aspects of the diseases that appear along the aging process and their impact on the quality of life of elderly individuals, as well as related biological, social, political and legal issues. The high rate of morbidity, atypical patterns of disease onset, the responses to treatment which can be slower and often unpredictable and the need for greater social support for elderly patients require special skills from health care professionals who work or intend to work at the service of the elderly. In this context, geriatricians and gerontologists need to expand their knowledge, focusing on preventive, clinical, therapeutic and social aspects of pathologies that arise with aging as well as to acquire/enhance the ability to work within interdisciplinary teams.
Professors Home time Lattes
CARLA HELENA AUGUSTIN SCHWANKE 22 years and 4 months Link
Concentration area Type Required
Biomedical Gerontology Master's Required
Biomedical Gerontology Doctorate Required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Meeting the longevity
COD Workload Description
1935L-02 30 The course seeks to provide students in the Biomedical Gerontology Program with personal contact or by videoconference with oldest-old (people aged 80 or over) participants of research of the Institute of Geriatrics and Gerontology or Open University for the third age (UNATI) aiming to understand their life trajectories in a holistic context. Students will have the opportunity to understand the aging process that each of the long-lived has passed since their life trajectory and current life situation within the context of active aging. Through the reports of the oldest old people, it will be possible to describe their life story, which may generate a publication according to the students' performance.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Memory and Aging
COD Workload Description
10538-02 30 This course aims to analyze the structures and mechanisms involved in memory processing, seeking to relate them with the biochemical and physiological alterations in the nervous system resulting from normal aging or neurodegenerative disorders.
Professors Home time Lattes
ELKE BROMBERG 31 years and 4 months Link
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Molecular Diagnosis of Aging-Associated Diseases
COD Workload Description
10590-02 30 This course will look at the basic principles on the molecular alterations that occur during aging and the main molecular techniques used in the diagnosis of infectious, contagious and chronic noncommunicable diseases that are common among the elderly.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Nervous System and Aging
COD Workload Description
10546-02 30 This course is intended to analyze the functional characteristics of the nervous system, seeking to relate them to changes resulting from normal aging or neurodegenerative disorders.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Neurobiology of Stress
COD Workload Description
19347-02 30 Explore the concepts of stress, health and disease, with a particular focus on historical and current literature. It will address multiple dimensions in the study of stress: genetics, epigenetics, molecular, cellular, physiological and cognitive, especially in the context of immunoendocrine and neuroscientific research. Study of the individual response to stress, as genetic and environmental factors play a role, as it translates into physiological and mental conditions and pathological or health conditions.
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
CTBMF Master's Not required
CTBMF Doctorate Not required
Clinical Psychology Master's Not required
Clinical Psychology Doctorate Not required
Clinical Stomatology Master's Not required
Clinical Stomatology Doctorate Not required
Dental Materials Master's Not required
Dental Materials Doctorate Not required
Dental Prosthetics Master's Not required
Dental Prosthetics Doctorate Not required
Endodontics Master's Not required
Endodontics Doctorate Not required
Human Cognition Master's Not required
Human Cognition Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Orthodontics and Facial Orthopedics Master's Not required
Orthodontics and Facial Orthopedics Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Psychology Doctorate Not required
Restorative Dentistry Master's Not required
Restorative Dentistry Doctorate Not required
Social Psychology Master's Not required
Social Psychology Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Assessment and psychological interventions in mental health This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus.
Psychosocial Processes: Practices and contexts This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge.
Cognition, brain and behavior This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience.
Well-being, health and quality of life This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Neuropsychology of Memory
COD Workload Description
30500-02 30 The human brain is a remarkably complex organic computer, which is not only capable of capturing a wide variety of sensory experiences, but also processes and stores information, and integrates selected fragments at the right time. Memory is used to store and keep past experiences and use them whenever necessary. Memory can be classified according to the duration and type of recall.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Neuroscience and aging
COD Workload Description
193BG-02 30 The course aims to provide postgraduate students with a in-depth knowledge of the neurobiological changes associated with aging. As well as the study of the main neuropathological characteristics of the aging associated with neurodegenerative diseases, in particular clinical research and of neuroimaging, in Alzheimer's Disease, Vascular Dementia, Frontotemporal Dementia and Dementia with Lewy Bodies.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Normal and Pathological Cognitive Aging: Clinical Implications
COD Workload Description
40503-02 30 This course looks at the fields of study in cognition and behavior in healthy aging and in neurodegenerative diseases, as well as the differential diagnosis of depression and cognitive impairment.
Professors Home time Lattes
IRANI IRACEMA DE LIMA ARGIMON 35 years and 11 months Link
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Patient Safety in the aging process
COD Workload Description
193BD-02 30 The subject addresses aging and Patient Safety based on the recommendations of the World Health Organization, the World Alliance for Patient Safety and the National Patient Safety Program, from the perspective of looking at and providing instruments for safe practices and for the involvement of the elderly and their family.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Pharmacology of Inflammation
COD Workload Description
23394-02 30 This course is intended to address several aspects related to the pharmacology of inflammation, namely: biochemical and molecular aspects of inflammatory events, with emphasis on pharmacological modulation. The main vascular and cellular alterations in response to different stimuli will be addressed. To follow are some topics of interest: (1) study of inflammatory response mediators, including those derived from mastocytes (histamine and serotonin), lipid mediators (prostanoids and leukotrienes), peptidic mediators (bradikinin and neurokinin), cytocines and growth factors, chemotactic factors, complement system mediators, nitric oxide, among others; (2) components of the resolution phase of inflammation, involving endogenous mediators related to the re-establishment of homeostasis and tissue repair; (3) main groups of cells involved in several phases of inflammation and their connection to immune response; (4) main receptors and signaling routes, as well as the components of intracellular transduction systems; (5) inflammation associated with infection and systemic inflammatory response; (6) correlation between inflammation and cancer; (7) regulatory aspects of the transcription of molecules implied in inflammatory response; (8) study of mechanisms of action of main drugs used in the treatment of inflammation; (9) chronic inflammatory diseases.
Professors Home time Lattes
MARIA MARTHA CAMPOS 18 years and 4 months Link
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
CTBMF Master's Not required
CTBMF Doctorate Not required
Clinical Psychology Master's Not required
Clinical Psychology Doctorate Not required
Clinical Stomatology Master's Not required
Clinical Stomatology Doctorate Not required
Dental Materials Master's Not required
Dental Materials Doctorate Not required
Dental Prosthetics Master's Not required
Dental Prosthetics Doctorate Not required
Endodontics Master's Not required
Endodontics Doctorate Not required
Human Cognition Master's Not required
Human Cognition Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Orthodontics and Facial Orthopedics Master's Not required
Orthodontics and Facial Orthopedics Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Psychology Doctorate Not required
Restorative Dentistry Master's Not required
Restorative Dentistry Doctorate Not required
Social Psychology Master's Not required
Social Psychology Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Assessment and psychological interventions in mental health This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus.
Psychosocial Processes: Practices and contexts This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge.
Cognition, brain and behavior This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience.
Well-being, health and quality of life This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Pharmacotherapy of Neurological and Psychiatric Disorders
COD Workload Description
1932A-01 15 Neuropharmacology is the study of the effect of drugs on the brain. The seminars explore the concepts and current research in cognitive neuroscience, including perception, brain structure and organization, cognition, memory and the functional basis of certain human neurological and psychiatric illnesses. (e.g. schizophrenia, depression and Narcolepsy). The purpose of this course is to provide students with an opportunity to acquire the theoretical and applied knowledge of neuropharmacology that will enable them to proceed into developing a career in neuropharmacology either in an academic institution, a research institute or in the industrial/business sector.
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Cellular and Molecular Biology Master's Not required
Cellular and Molecular Biology Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Pharmaceutical Biotechnology Professional Master's Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Physiology of Aging
COD Workload Description
20599-02 30 The course will address the impact that the aging process has on different human physiological systems, focusing on aspects of the decline of their functions.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Practice in Medical Research Software
COD Workload Description
63348-04 60 Knowing how to use computer tools is fundamental for conducting research in health. This course is intended to explore, in a practical way, important software for medical research. The focus will be on online resources, spreadsheets, graphic programs, statistical programs, word processors, and bibliographic reference management.
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
CTBMF Master's Not required
CTBMF Doctorate Not required
Cellular and Molecular Biology Master's Not required
Cellular and Molecular Biology Doctorate Not required
Clinical Psychology Master's Not required
Clinical Psychology Doctorate Not required
Clinical Stomatology Master's Not required
Clinical Stomatology Doctorate Not required
Dental Materials Master's Not required
Dental Materials Doctorate Not required
Dental Prosthetics Master's Not required
Dental Prosthetics Doctorate Not required
Endodontics Master's Not required
Endodontics Doctorate Not required
Human Cognition Master's Not required
Human Cognition Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Orthodontics and Facial Orthopedics Master's Not required
Orthodontics and Facial Orthopedics Doctorate Not required
Pediatrics Master's Not required
Pediatrics Inter-institutional doctorate degree Not required
Pediatrics Doctorate Not required
Psychology Doctorate Not required
Restorative Dentistry Master's Not required
Restorative Dentistry Doctorate Not required
Social Psychology Master's Not required
Social Psychology Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Assessment and psychological interventions in mental health This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus.
Psychosocial Processes: Practices and contexts This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge.
Cognition, brain and behavior This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience.
Well-being, health and quality of life This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Preventive Geriatrics
COD Workload Description
10512-02 30 Preventive Geriatrics is the science and art of preventive diseases, extending life with quality and promotion of health and mental efficiency of aging individuals. This course is a valuable source of insights for the development and dissemination of knowledge for individuals, in the sense that once they age, they can have better health conditions and safety, and be active, productive, be able to avoid diseases and have a successful elderly life with functional anatomy or self-sufficiency and independence.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Principles of Molecular Biology
COD Workload Description
63416-02 30 This course is intended to introduce students to the main theoretical and practical concepts of the area of molecular biology, applied to the health area, focusing on the main current scientific topics of molecular biology therapies.
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
CTBMF Master's Not required
CTBMF Doctorate Not required
Cellular and Molecular Biology Master's Not required
Clinical Psychology Master's Not required
Clinical Psychology Doctorate Not required
Clinical Stomatology Master's Not required
Clinical Stomatology Doctorate Not required
Dental Materials Master's Not required
Dental Materials Doctorate Not required
Dental Prosthetics Master's Not required
Dental Prosthetics Doctorate Not required
Endodontics Master's Not required
Endodontics Doctorate Not required
Human Cognition Master's Not required
Human Cognition Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Orthodontics and Facial Orthopedics Master's Not required
Orthodontics and Facial Orthopedics Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Psychology Doctorate Not required
Restorative Dentistry Master's Not required
Restorative Dentistry Doctorate Not required
Social Psychology Master's Not required
Social Psychology Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Assessment and psychological interventions in mental health This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus.
Psychosocial Processes: Practices and contexts This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge.
Cognition, brain and behavior This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience.
Well-being, health and quality of life This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Public Health and Aging
COD Workload Description
30501-02 30 This course seeks to promote a discussion in the area of Public Health and Aging, in light of the National and International Public Policies which aim to improve the access of senior citizens to health care actions and services. It also seeks to support a critical analysis of health programs and services by offering insights that can be applied to the construction of more effective policies in the field of Public Health and Aging.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Qualitative Methods in the Investigation of Aging
COD Workload Description
10539-02 30 The course covers the approaches to qualitative research and complements it with quantitative data data in order to raise professionals'/researchers' awareness to the analysis of paradigmatic orientations underpinning research results and on attention to scientific criteria.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Qualitative Methods in the study of aging
COD Workload Description
1933M-02 30 Study on social research theory and methodology and its relevance for the production of knowledge in the area of aging. Analysis of scientific criteria and particularities of qualitative research in the areas of health sciences. Apprehension of the investigative cycle, with emphasis on methodological procedures, including the elaboration of the research project, techniques, instruments and investigative procedures for the collection and analysis of qualitative data. The mixed focus on research. Complementarity of quantitative and qualitative data. Grounded theory of data. Elaboration of ethnographic questions. Focus groups. Content analysis, discourse analysis and discursive textual analysis. Ethical aspects of research.
Professors Home time Lattes
PATRICIA KRIEGER GROSSI 24 years and 4 months Link
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Social Work, Policies and Social Processes Master's Not required
Social Work, Policies and Social Processes Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Social Work, Social Security and Social Policies This line encompasses studies and research on social protection systems, social security, and their connection to the State and civil society. It fosters a discussion on health, social security and social assistance, income transfer, food security policies and unemployment insurance. It addresses studies on territoriality and housing, educational policies, policies for the elderly, for women, for children and teenagers, for youths, for the homeless, for the disabled, among other groups and areas. It includes debates on the production of knowledge, and interdisciplinary work and of the social worker in these areas, as well as the assessment of public policies and studies on public funding and on the public-private relationship.
Social work, human rights, inequalities and resistance This line encompasses studies and investigations on human rights and their historic characteristics. The protection systems of human rights and their connection with the State and the civil society, violations of rights as well as the advances and backlashes in the affirmation of rights. It will also address studies on social policies focused on historically vulnerable peoples, in terms of human rights: black and indigenous peoples, lesbians, gays, bisexuals, transvestites and transsexuals, the elderly, youths, children and teenagers, the disabled, the homeless, women, rural and city workers, refugees and immigrants, etc. It will also investigates inequality and resistance processes and their repercussions on how these social subjects lead their lives, in view of different social markers. Additionally, this line includes studies related to punitive power of the State in the prison system, the justice system and public safety, and restorative justice. It includes as well, studies on the multiple expressions of violence and the different strategies for fighting it. The line also addresses studies on professional work (of social workers in an interdisciplinary way) in these areas and its contributions to the scientific area of Social Work and related fields, on the production of knowledge in these areas.
Social Work, Teaching and Training This line encompasses studies and investigations on the foundations of Social Work, on social question and issues about the method. It includes studies on the ethical-political, theoretical-methodological and technical-operational axes of the profession and on Social Work training and its connection with the actions conducted by social workers, their duties and competencies. It includes studies on the curriculum guidelines of the ABEPSS (Brazilian Association for Study and Research on Social Work) and the cores for training in Social Work and the guidelines for Graduate programs. It addresses studies on teaching modalities, on teaching and training in undergraduate and graduate programs, on pedagogical strategies, on theory and methodology of research, on ethics and ethical-political project, on continuing education, on supervision and internship, on advising and assessment in undergraduate and graduate programs, on school and university management and on work and knowledge production in these areas.
Social Work, Labor and Social Processes This line encompasses studies and investigations on labor as an ontological category, the labor processes, labor relationships and conditions in the capitalist production model, State, political economy, productive restructuring and the changes in the labor environment, employment and unemployment, socio-occupational spaces and the Social Workers labor in schools, health care, social services, local power, public sector, third sector and private sector, interdisciplinary work, occupational health, concrete and abstract work and the alienation processes, labor and income policies, cooperative work and solidarity economy, among other production strategies, relationships and production models. This line also addresses the study of social processes such as participation, social management processes, planning, networking, councils, social movements, popular organizations, trade union movements and, in addition to that, processes such as poverty, prejudice, racism, violence, among others. It also addresses studies on interdisciplinary work and the social worker actions for strengthening and fighting these processes, and the contributions of Social Work to these areas in terms of production of knowledge.
Research Methodology: Methods and techniques
COD Workload Description
7334J-01 15 Designing and adhering to the appropriate methodology is fundamental for improving the quality of research. The methodology may differ from problem to problem, yet the basic approach towards research remains the same.
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
CTBMF Master's Not required
CTBMF Doctorate Not required
Clinical Psychology Master's Not required
Clinical Psychology Doctorate Not required
Clinical Stomatology Master's Not required
Clinical Stomatology Doctorate Not required
Dental Materials Master's Not required
Dental Materials Doctorate Not required
Dental Prosthetics Master's Not required
Dental Prosthetics Doctorate Not required
Endodontics Master's Not required
Endodontics Doctorate Not required
Human Cognition Master's Not required
Human Cognition Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Orthodontics and Facial Orthopedics Master's Not required
Orthodontics and Facial Orthopedics Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Psychology Doctorate Not required
Restorative Dentistry Master's Not required
Restorative Dentistry Doctorate Not required
Social Psychology Master's Not required
Social Psychology Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Assessment and psychological interventions in mental health This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus.
Psychosocial Processes: Practices and contexts This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge.
Cognition, brain and behavior This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience.
Well-being, health and quality of life This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Research Practice
COD Workload Description
20534-03 45 This course is intended to provide a critical reflection on the process of designing an original paper as well as a critical reading of papers. The strategies for designing each one of the topics that form an original paper (title, summary, introduction, methods, results, discussion and conclusion) will be looked at in both a theoretical and practical way. Additionally, searching, archiving and reference management will be discussed.
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Cellular and Molecular Biology Master's Not required
Cellular and Molecular Biology Doctorate Not required
Clinical Psychology Master's Not required
Clinical Psychology Doctorate Not required
Human Cognition Master's Not required
Human Cognition Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Psychology Doctorate Not required
Social Psychology Master's Not required
Social Psychology Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Assessment and psychological interventions in mental health This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus.
Psychosocial Processes: Practices and contexts This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge.
Cognition, brain and behavior This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience.
Well-being, health and quality of life This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Scientific Research Dynamics and Policies
COD Workload Description
7311B-02 30 This course intends to foster discussions on research policies in Brazil, including the assessment criteria employed by CAPES as well as scientometrics criteria. It also discusses the means for obtaining funding for scientific projects with an eye to meeting the different criteria set forth in specific projects. Additionally, one of the goals of the course is to discuss the scientific career both in Brazil and overseas and the possibilities for getting into the market. The course will discuss the differences between the areas of concentration as well as regional differences and other controversial topics in science. The peer-review process will be addressed, for both projects and scientific papers submitted to indexed journals. Part of the classes will be devoted for discussions on the ethical aspects of research, including issues such as plagiarism, co-authorship, publication of negative results, among others. Students will receive specific training to properly advise final papers as well as theses and dissertations.
No offer for current semester
Concentration area Type Required
Biochemical and Molecular Pharmacology Master's Not required
Biochemical and Molecular Pharmacology Doctorate Not required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
CTBMF Master's Not required
CTBMF Doctorate Not required
Cellular and Molecular Biology Master's Not required
Cellular and Molecular Biology Doctorate Not required
Clinical Psychology Master's Not required
Clinical Psychology Doctorate Not required
Clinical Stomatology Master's Not required
Clinical Stomatology Doctorate Not required
Dental Materials Master's Not required
Dental Materials Doctorate Not required
Dental Prosthetics Master's Not required
Dental Prosthetics Doctorate Not required
Ecology and Evolution of Biodiversity Master's Not required
Ecology and Evolution of Biodiversity Doctorate Not required
Endodontics Master's Not required
Endodontics Doctorate Not required
Human Cognition Master's Not required
Human Cognition Doctorate Not required
Medical Practice Master's Not required
Medical Practice Doctorate Not required
Nephrology Master's Not required
Nephrology Doctorate Not required
Neurosciences Master's Not required
Neurosciences Doctorate Not required
Orthodontics and Facial Orthopedics Master's Not required
Orthodontics and Facial Orthopedics Doctorate Not required
Pediatrics Master's Not required
Pediatrics Doctorate Not required
Psychology Doctorate Not required
Restorative Dentistry Master's Not required
Restorative Dentistry Doctorate Not required
Social Psychology Master's Not required
Social Psychology Doctorate Not required
Surgical Practice Master's Not required
Surgical Practice Doctorate Not required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment and inflammation.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Ecology and Conservation This line of research encompasses projects focusing on ecological relationships among organisms and with their environment, including studies of autecology, ecophysiology, behavior, population dynamics and community ecology, as well as projects aiming to provide scientific bases for biodiversity conservation strategies.
Systematics and Evolution The research line brings together projects related to the evolution of biodiversity, including studies in phylogenetic systematics (using morphological and molecular data, including phylogenomics), taxonomy, comparative morphology, biogeography, evolutionary genetics, and comparative genomics.
The research line brings together projects focused on the use of large amounts of information ('big data') and the development of innovative data mining and analysis methodologies (e.g., employing machine learning) to investigate issues related to the characterization, monitoring, and conservation of biodiversity
The research line encompasses projects aimed at applying ecological data, biodiversity component analyses, and/or interdisciplinary studies to solve problems with more direct socio-environmental and/or economic impact. This includes studies in the fields of ecotoxicology and environmental microbiology with a focus on the characterization, monitoring, and mitigation of environmental impacts, as well as the development of more sustainable agricultural methods using components of Brazil's native biodiversity. It also includes projects aimed at developing innovative products from biodiversity sources and/or integrating biodiversity analyses into regional economic development models with a focus on environmental sustainability.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Training and Faculty Development in Health
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Technological Innovations in the Health Area Curently, we are seeing worldwide the fast development of technologies, proceedings and medicines focus at the most effective treatment of diseases and the restoration of health. This accelerated step with which medical knowledge progresses makes it necessary to create a new mentality in medical training, stimulating curiosity, the active search for knowledge and constant updating. The number and complexity of the scientific processes that lead to this evolution are also worthy of attention, both due to the need for training to understand them, as well as the work opportunity they represent for doctors in general.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
The central nervous system (CNS) formation stages can be considered a great concert with the regency of different signaling molecules that trigger a cascade of dependent and complementary processes until the formation of all CNS structures as well as their different functionalities. The human brain is a puzzle of more than 100 billion pieces that must be accurately directed to its unique and specific location. The studies of Molecurar Bases of Embryonic Neurogenesis presents a comprehensive view of understanding the CNS, from its embryonic formation to neurogenesis in the adult brain, guiding clinical and pathological situations related to cerebral malformations and new therapeutic alternatives for CNS recovery. The use of molecular techniques as next-generation sequencing (NGS), super arrays, relative expression, genotyping, etc., are used to describe signaling pathways, genesis of pathologies, and application of precision medicine for the treatment of various diseases. The cell reprogramming at the embryonic level through the generation of induced pluripotent stem cells (iPSC) helps to understand embryonic neurogenesis and screening of new drugs for the treatment of alterations during the formation of the central nervous system and its associated pathologies
Artificial Intelligence in Healthcare Fluency in oral reading is a crucial skill for children and adolescents, involving the ability to read a text with accuracy, appropriate expression, and at a determined pace. Artificial intelligence has enabled considerable advances in activities that previously required time and attention from specialized professionals, also offering the advantage of impartial evaluation. Moreover, a significant portion of students in Brazil presents literacy difficulties associated with reading skills and lacks adequate assistance and diagnosis for conditions such as dyslexia. This research line aims to encompass research projects at the intersection of health, education, and artificial intelligence. The studies seek to investigate tools for assessing oral reading through innovative technologies, which can be used by health professionals in collaboration with educators. These tools aim to assist in identifying the level of reading development, factors influencing these skills, association with academic performance, early screening of signs of difficulties and disorders affecting reading fluency, differential diagnoses, as well as the appropriate medical/educational conduct.
Assessment and psychological interventions in mental health This line of research concentrates studies related to mental health outcomes based on different theories and methods in Clinical Psychology. It aims at understanding psychological processes and building and adapting instruments and interventions with a psychotherapeutic and psychoeducational focus.
Psychosocial Processes: Practices and contexts This line of research concentrates studies on psychosocial phenomena and vulnerability processes in different contexts, such as education, public health, work, politics and justice. It aims to develop strategies for assessment and intervention with individuals, groups and organizations based on theoretical-methodological approaches that articulate different perspectives from Social Psychology and other fields of knowledge.
Cognition, brain and behavior This line of research focuses on basic and applied studies of cognition and its behavioral and neurobiological implications. We seek to investigate neurocognitive and psychobiological processes and their relationship with behavior, development, learning and mental health. Research approaches involve theoretical and experimental models and instruments from neuropsychology, neurobiology and neuroscience.
Well-being, health and quality of life This line of research concentrates studies that use an interdisciplinary approach on the relationship between mental health and lifestyle, understood as the set of behaviors related to food, physical activity, sleep, spirituality, financial well-being, well-being occupational and social relationships. The line aims at building basic and applied knowledge for evaluation and intervention in the prevention and promotion of quality of life and its different domains.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Social Gerontology
COD Workload Description
10518-02 30 This course will look at the basic concepts on Social Gerontology, such as: concepts, the issue of an aging society, social policies for the elderly, myths about aging, social legislation (National Policy for the Elderly, Elderly Statute). Global aging and the international approach to it in the Vienna (1982) and Madrid (2002) Assemblies. It looks at the issues of transitions inherent to aging, such as the feminization of old age, retirement, institutionalization, social safety networks, the prospect of active aging and the interface with Social Work and related fields.
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
COD Workload Description
193BC-03 45
No offer for current semester
Concentration area Type Required
Biomedical Gerontology Master's Not required
Biomedical Gerontology Doctorate Not required
Research line Description
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.