Célia Regina R da S Carlini

Schools: School of Medicine
Graduate Programs: Biomedical Gerontology Graduate Program Cellular and Molecular Biology Graduate Program Medicine and Health Sciences Graduate Program
Publications: Orcid ResearcherID

Introduction

B.Sc degree in Biological Sciences - Medical modality, from Universidade Federal de São Paulo (1978), M.Sc. (1981) and Ph.D. (1985) in Molecular Biology - Protein Chemistry from Universidade Federal de São Paulo (UNIFESP). Member of the Brazilian Academy of Sciences (elected 2009). Presently, Senior Researcher at the Brain Institute (InsCer), Pontificia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil. Research experience in Biochemistry, focusing on Proteins, including the following subjects: canatoxin, ureases, lectins, proteolytic enzymes and cognate inhibitors, blood clotting, platelet aggregation, inflammation, neurotoxins, insecticidal, antifungal, pore-forming and ion channel proteins and peptides. Presently, her research team is focused on studying: 1) non-enzymatic properties of ureases, including antifungal, insecticidal, and, particularly, their neurotoxic activities; 4) urease-derived biologically active peptides; 3) the role of microbial ureases as virulence factor of the bacteria Helicobacter pylori and Proteus mirabilis, 4) neuroinflammation and the role of eicosanoids.

Areas of interest

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Themes

Concentration Areas and Lines Research

Biomedical Gerontology

- Biological Aspects of Aging

Cellular and Molecular Biology

- Cellular and Molecular Neurobiology

Neurosciences

- Neurotoxic activity of ureases and derived peptides

Research Structures

Research Group

- Neurotoxins