Courses

APPLIED BIOINFORMATICS
COD Workload Description
73163-03 45 This course will, among other things, address the following topics: Introduction of Bioinformatics as an interdisciplinary science; introduction to the concepts of technological singularity; elementary algorithms; introduction to the concepts of programming; installation of Python; the use of an integrated environment of development; implementation of equations on Python; programming strategies; relevant concepts of Molecular Biology for Bioinformatics; string manipulation; design of string manipulation software; reading and writing of files on Python; flow control; quest for sequential motives; biological databases GenBank; Protein Data Bank; BioPython; object-oriented programming; regular expressions; discussion of research projects in Bioinformatics.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Advanced Topics in Biosciences I
COD Workload Description
19515-01 30 Study and discussion of current issues in biosciences, which have outstanding scientific, technological and/or social relevance. Understanding of selected topics through reading and discussing scientific papers and/or conducting experiments.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Advanced Topics in Biosciences II
COD Workload Description
19516-01 15 Study and discussion of current issues in biosciences, which have outstanding scientific, technological and/or social relevance. Understanding of selected topics through reading and discussing scientific papers and/or conducting experiments.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Advanced Topics in Biosciences III
COD Workload Description
19517-02 30 Study and discussion of current issues in biosciences, which have outstanding scientific, technological and/or social relevance. Understanding of selected topics through reading and discussing scientific papers and/or conducting experiments.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Astrobiology
COD Workload Description
19504-04 60 Big bang theory; origin of the solar system; origin of life; molecular scenarios for the origin of life; Miller experiment; prebiotic peptides; computer simulation of prebiotic peptides; RNA world; habitable zones in the solar system; extreme environments; Mars and life; space probes; icy bodies in the solar system and beyond; detection of exoplanets; the nature of exoplanets; extraterrestrial intelligence; search for extraterrestrial intelligence; SETI project; Drake equation; Seager equation; presentation of technological singularity and its relation with extraterrestrial intelligence; research projects in Astrobiology.
Professors Home time Lattes
WALTER FILGUEIRA DE AZEVEDO JUNIOR 14 years and 3 months Link
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
BIO-INSPIRED COMPUTING
COD Workload Description
73178-04 60 To follow is a list of topics this course will cover: Introduction to Bio-inspired computing; Description of Python functions for use in Bio-inspired computing; Study of techniques and methods for use in scientific computing libraries on Python: NumPy, SciPy and Matplotlib; Description of optimization problems; Introduction to the study of genetic algorithms; Introduction to the study of evolutionary algorithms for optimization problems; Introduction to the study of evolutionary simulation in computers; Description of differential evolution algorithms; Description of the implementation of evolutionary algorithms on Python; Description of molecular docking problems; Description of the use of evolutionary algorithms for simulation of molecular docking; Introduction to the study of neural networks; Description of the implementation of neural networks on Python; Introduction to the study of collective behavior-based algorithms; Description of the implementation of collective behavior-based algorithms on Python; Presentation of scientific projects in Bio-inspired computing.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
BIOCHEMISTRY OF PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES
COD Workload Description
73164-02 30 This course will address the study of the structure and operation of the main biological compounds in the context of physiological and pathological processes.
Professors Home time Lattes
CARLA DENISE BONAN 20 years and 8 months Link
ROSANE SOUZA DA SILVA 15 years and 8 months Link
Concentration area Type Obligatoriness
Biochemical and Molecular Pharmacology Master's Don't Required
Biochemical and Molecular Pharmacology Doctorate Don't Required
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Medical Practice Master's Don't Required
Medical Practice Doctorate Don't Required
Nephrology Master's Don't Required
Nephrology Doctorate Don't Required
Neurosciences Master's Don't Required
Neurosciences Doctorate Don't Required
Surgical Practice Master's Don't Required
Surgical Practice Doctorate Don't Required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Preclinical neuropharmacology This line of research is concerned with Pre-Clinical Neuropharmacology.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Respiratory Diseases / Exhaled nitric oxide and others markers of inflammation This line of research is intended to assess the role of expired nitric oxide as an inflammation marker.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Respiratory Diseases / Smoking and smoking-related diseases This line of research will address the determining factors of success/failure in smoking cessation; it will assess the role of genetics in the experimentation, maintenance and cessation of smoking; it will test the efficacy of different therapies.
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Training and Development for Teachers in Health Sciences This line of research will enable the production of scientific and technological research and the provision of Master's and Doctoral degrees as well as the conduction of Postdoc research in the area of Health Care Education.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Mechanisms of memory consolidation This line of research will look at the role of the central histaminergic system in the basolateral amygdala and in the hippocampus in the consolidation of aversive and non-aversive memory. It will also look at the influence of the treatment relying on a histidine decarboxylase inhibitor.
Developmental neurology This line of research will deal with the ontogenesis and bioelectrogenesis of the Central Nervous System (clinical aspects and animal model), sleep studies and its disorders through the assessment of clinical and neurophysiological characteristics, thus laying the foundations for the understanding of sleep medicine in childhood, and the normal and abnormal development in early childhood.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Cholinergic versus non-cholinergic components of memory The purpose of this line of research is to determine the components of memory deficits observable in transgenic rats incapable of expressing the fast transporter of hippocampal acetylcholine in different degrees. This can be applied to the treatment of the Alzheimer's disease with pro-collinergic drugs among others.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Synaptic tagging of extinction The generation of weak LTP in a dendrite of pyramidal cells of the hippocampus can increase its potential by the LTP produced in another distant dendrite. This is called synaptic tagging and is due to the tagging of the first synapsis (tag) by a local protein which attracts another generated by the second synapsis (capture).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Childhood epilepsy This line of research will address epilepsy in childhood.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
Cell Terapy (Clinicals and experimental models, Regeneration and Tissue engineering, stem cells) This line of research will look at clinical and experimental models focused on the development of stem cells therapies, nervous regeneration and the use of stem cells in surgeries.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Peripheral nerve (Clinical and experimental models, nerve regeneration, growth factors, stem cellls) Tissue Engineering (TE) is concerned with the study of new forms of tissue production to be used in reconstructive surgeries. It covers all methods and efforts made in order to create or induce the formation of tissues in a specific location.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
BIOLOGICAL BASIS OF THE NERVOUS SYSTEM FUNCTIONING
COD Workload Description
73140-03 45 This course is intended to analyze the several levels of organization of the nervous system by integrating cellular and molecular aspects with sensory, motor and superior functions.
Professors Home time Lattes
ELKE BROMBERG 26 years and 8 months Link
PATRICIA FERNANDA SCHUCK 1 year and 6 months Link
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
BIOLOGY OF TUMORS
COD Workload Description
73157-02 30 This course is intended to provide students with deeper and new insights into the relevant aspects of biology of tumors, from development to therapies.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
CELL BIOLOGY OF PLANTS: ADAPTIVE STRATEGIES
COD Workload Description
73161-03 45 To follow is a list of topics this course will look at: Characteristics of plant cells. The correlation between the plant's cellular/molecular mechanisms with strategic ones to different biotic agents of stress. Biotechnological strategies to minimize biotic stresses. The topics will be delivered in the form of lectures.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
CELL BIOLOGY: ADVANCES AND APPLICATIONS
COD Workload Description
73127-04 60 This course is intended to provide students with insights into a deeper understanding and application of advanced knowledge of the biology of prokaryotic and eukaryiotic cells of animals and plants, as well as the genetic variability and the importance of natural and domesticated species, thus giving them conditions to assess and critique the natural evolutionary process and the limits of human intervention in the conduction of evolutionary processes of economic interest.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Required
Cellular and Molecular Biology Doctorate Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
COMPLEXITY AND INTERDISCIPLINARITY STUDIES
COD Workload Description
73153-02 30 This course will provide a reflection upon complex issues and an interdisciplinary approach in research and teaching. It will cover the characteristics, advantages and disadvantages of this approach. It will lead to the analysis of the main challenges of interdisciplinary approach: peculiarities of taxonomy and epistemology within the areas, identification of common conceptual territories, the co-existence of compartmentalized structures with new highly interactive structures, assessment of interdisciplinary research productivity or performance. It will lastly lead to the planning of courses of action to overcome these challenges.
Professors Home time Lattes
CARLOS GRAEFF TEIXEIRA 27 years and 7 months Link
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Cellular and Molecular Basis of Neurodegeneration
COD Workload Description
19502-02 30 Central nervous system cell functions. Cell signaling. Cell death. Oxidative stress and neurodegeneration. Bionergetics and neurodegeneration. Neuroinflammation and neurodegeneration. Neurotoxicity and neuroprotection.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Comparative Genomics
COD Workload Description
73196-02 30 The topics this course addresses are as follows: Comparative analysis of genomes, with focus on nuclear genomes of eukaryotes; Comparative mapping of genomes; Structure of genomes and its functional consequences; Genomic architecture and variation in the number of copies of genomic segments; Evolution of the structure of genomes in different bodies; Current methods for sequencing, assembling and annotation of eukaryotic genomes; Evolutionary analysis involving genomic scale data; phylogenomics and population genomics.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Zoology Master's Don't Required
Zoology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Ecology and Conservation This line of research includes projects related to the study of the ecological relationships of animals in the broadest sense, including autoecology, ecophysiology, behavior, parasitology, population dynamics, and conservation studies.
Systematic and Biodiversity This line of research brings together projects related to the study of biodiversity in all its comparative aspects, such as Taxonomy, Systematics (morphological and molecular), morphology and inventories, in the different taxonomic groups.
Applied Zoology This line will look at biochemical, physiological and natural history studies, among others, of organisms that have a sanitary, economic, social and/or environmental interest.
Computational Molecular Biophysics
COD Workload Description
7311C-04 60 The topics this course addresses are as follows: Introduction to computational molecular biophysics; Molecular models; Computer-simulated methods; Theoretical foundations of the molecular dynamics method; Forms of potential functions; Harmonic and torsional geometric potentials; Van de Waals force; Eletrostactics; Methods of optimization of molecular geometries; Implicit and explicit solvent molecular dynamics simulations; Production of dynamics trajectories; Dynamics of polypeptides and proteins; Analysis of local and global conformational changes in polypeptides and proteins; Data science applied to computational simulations; Applications of computational molecular biophysics; Micro-protein folding.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
DNA metabarcoding for biodiversity and conservation studies
COD Workload Description
19506-01 15 Understand principles, methods and applications of the DNA metabarcoding technique in biodiversity and conservation studies. Bioinformatic data analyses including the development of pipelines to obtain diversity inventories or interpretable ecological data. Understand other techniques that use high-throughput sequencing such as metagenomics.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Zoology Master's Don't Required
Zoology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Ecology and Conservation This line of research includes projects related to the study of the ecological relationships of animals in the broadest sense, including autoecology, ecophysiology, behavior, parasitology, population dynamics, and conservation studies.
Systematic and Biodiversity This line of research brings together projects related to the study of biodiversity in all its comparative aspects, such as Taxonomy, Systematics (morphological and molecular), morphology and inventories, in the different taxonomic groups.
Applied Zoology This line will look at biochemical, physiological and natural history studies, among others, of organisms that have a sanitary, economic, social and/or environmental interest.
Environmental microbiology
COD Workload Description
19503-02 30 Study of the microbial communities of different ecosystems, addressing their composition, advanced topics on the interactions involving species of prokaryotes, eukaryotes and viruses, as well as survey methods a and their biotechnological potential.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
FLOW CYTOMETRY
COD Workload Description
19513-02 30 Basic and advanced theoretical concepts of flow cytometry. Understanding and functioning of different devices, usual applications such as immunophenotyping, cell cycle, cell death, detection of phosphorylated proteins, quantification of cytokines, mitochondrial function measurements and data analyses.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
FORENSIC GENETICS
COD Workload Description
73165-04 60 This course will focus on the development of abilities and competences for the design, interpretation, discussion and conduction of research into the human genome with an eye to individual molecular identification for its application into forensic investigations.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Fundaments and Applications in Flow Cytometry
COD Workload Description
19501-02 30 The aim of the course is to provide students with basic theoretical and practical concepts of flow cytometry; such as operation and maintenance, applications in common techniques such as immunophenotyping, cell cycle, cell death, detection of phosphorylated proteins, quantification of cytokines, among others.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
IMMUNOLOGY
COD Workload Description
73123-04 60 This course is intended to enable students to understand and apply their knowledge of immunology and the different vaccination strategies used up until today.
Professors Home time Lattes
MOISES EVANDRO BAUER 20 years and 3 months Link
CARLOS ALEXANDRE SANCHEZ FERREIRA 18 years and 3 months Link
FLORENCIA MARIA BARBE TUANA 1 year and 7 months Link
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
IN SILICO DRUG DISCOVERY AND DEVELOPMENT
COD Workload Description
73138-02 30 This course will address the molecular objects and goals of molecular design, molecular representation, formats used for molecular representation (small molecules and proteins), molecular and functional databases, ligand-protein interaction, molecular and thermodynamic bases of ligand-protein interaction, the empirical scoring function, molecular docking algorithms, virtual screening of drugs, Lipinski's and Veber's rules for the selection of potential drugs, development of anti-HIV drugs, development of anti-cancer drugs, development of anti-bacterial drugs and discussion of projects for the development of structure-based drugs.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
INTEGRATION SEMINAR I
COD Workload Description
73126-01 15 This course will consist of the delivery of scientific seminars by researchers, professors or graduate students in the several basic and applied areas of Biological Sciences, with emphasis on Cellular and Molecular Biology. After the topics have been delivered, students will be encouraged to discuss them.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Required
Cellular and Molecular Biology Doctorate Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
INTEGRATION SEMINAR II
COD Workload Description
73132-01 15 This course will consist of the delivery of scientific seminars by researchers, professors or graduate students in the several basic and applied areas of Biological Sciences, with emphasis on Cellular and Molecular Biology. After the topics have been delivered, students will be encouraged to discuss them.
Professors Home time Lattes
CELIA REGINA RIBEIRO DA SILVA CARLINI 6 years and 3 months Link
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Required
Cellular and Molecular Biology Doctorate Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Inborn Errors of Metabolism
COD Workload Description
19514-02 30 The study and diagnosis of inborn errors of metabolism. The study of fatty acid oxidation defects, organic acidurias, aminoacidopathies, lisosomal storage diseases, and peroxisomal disorders. Investigation about the pathophysiology of inborn errors of metabolism.
Professors Home time Lattes
PATRICIA FERNANDA SCHUCK 1 year and 6 months Link
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Integrity in Scientific Writing and Presentation
COD Workload Description
19518-04 60 The main goals of this course are to improve students’ skills associated with writing scientific papers for high-quality journals and those necessary to give oral presentations at scientific meetings. Classes will be based on the discussion of topics related to writing skills, including manuscript structure, goals and writing strategies. Ethical aspects of scientific practices regarding authorship, conflict of interests and data analysis and preparation are also discussed. Key aspects of oral presentation and how to organize and give effective talks will also be discussed.
Professors Home time Lattes
MONICA RYFF MOREIRA ROCA VIANNA 14 years and 8 months Link
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Zoology Master's Don't Required
Zoology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Ecology and Conservation This line of research includes projects related to the study of the ecological relationships of animals in the broadest sense, including autoecology, ecophysiology, behavior, parasitology, population dynamics, and conservation studies.
Systematic and Biodiversity This line of research brings together projects related to the study of biodiversity in all its comparative aspects, such as Taxonomy, Systematics (morphological and molecular), morphology and inventories, in the different taxonomic groups.
Applied Zoology This line will look at biochemical, physiological and natural history studies, among others, of organisms that have a sanitary, economic, social and/or environmental interest.
MASS SPECTROMETRY APPLIED TO BIOLOGICAL SYSTEMS
COD Workload Description
73152-04 60 This course will address the aspects related to the analytical technique of mass spectrometry focusing on applications of biological systems.
Professors Home time Lattes
ANDRE ARIGONY SOUTO 21 years and 8 months Link
CRISTIANO VALIM BIZARRO 7 years and 8 months Link
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
METABOLIC BASIS OF PLANT GROWTH
COD Workload Description
73191-03 45 To follow is a list of topics this course will address: The metabolic regulation of processes related to plant growth, such as the metabolism of carbohydrates and nitrogen. Metabolic and molecular aspects of the actions of plant hormones. Endocrine signaling in plant growth. Molecular physiology in the production, transport and use of mineral nutrients. Metabolism of growth promotion through biotic interactions.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
MOLECULAR BIOLOGY: ADVANCES AND APPLICATIONS
COD Workload Description
73120-04 60 This course is intended to provide students with insights for the understanding and application of the fundamental and advanced topics related to molecular biology, the basic genetic mechanisms (DNA, genes, RNA and protein) and to biotechnology
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Required
Cellular and Molecular Biology Doctorate Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
MOLECULAR TOPICS IN BACTERIOLOGY
COD Workload Description
73154-02 30 This course is intended to equip students to take part in discussions on bacteriology at the molecular level, including topics in bacterial cytology, physiology, and genetics, as well as to understand the bacterial interactions with their host, which are relevant for the understanding of pathogenicity.
Professors Home time Lattes
SILVIA DIAS DE OLIVEIRA 17 years and 3 months Link
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
MOLECULAR TOPICS IN PARASITOLOGY
COD Workload Description
73151-02 30 This course will deal with the molecular aspects involved in the interaction between parasite-host, by using models to study typical characteristics of parasitic life, virulence control mechanisms and strategies for diagnosis and immunization in parasitology.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Methods and Analyses in Biological Systems
COD Workload Description
73121-04 60 This course is intended to enable students to understand and apply the laboratory techniques that are employed in biological research as well as to select, organize and analyze data resulting from scientific research.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
NEURODEGENERATIVE DISEASES: CELLULAR AND MOLECULAR ASPECTS
COD Workload Description
73129-02 30 This course is intended to provide students with a deeper understanding of cellular and molecular bases of pathologies associated with neurodegeneration, and events leading to it, by discussing the selective neuronal vulnerability. As well as that, it will address animal models and possible targets for therapeutic intervention.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Pharmacological and Toxicological Basis of Therapy
COD Workload Description
19505-02 30 This course aims to increase knowledge in the field of pharmacology and toxicology, with particular emphasis on biochemical and molecular aspects that influence the action of drugs. It will be addressed aspects of general pharmacology, such as pharmacokinetics and pharmacodynamics. These aspects will be studied both at the level of basic and applied science, seeking to integrate these two areas of pharmacological knowledge. It will be addressed the stages of intoxication, exposure, toxicokinetic, toxicodynamic and clinical, and the dose / response curve.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Pharmacotherapy of Neurological and Psychiatric Disorders
COD Workload Description
1932A-01 15 Neuropharmacology is the study of the effect of drugs on the brain. The seminars explore the concepts and current research in cognitive neuroscience, including perception, brain structure and organization, cognition, memory and the functional basis of certain human neurological and psychiatric illnesses. (e.g. schizophrenia, depression and Narcolepsy). The purpose of this course is to provide students with an opportunity to acquire the theoretical and applied knowledge of neuropharmacology that will enable them to proceed into developing a career in neuropharmacology either in an academic institution, a research institute or in the industrial/business sector.
Professors Home time Lattes
JOCIANE DE CARVALHO MYSKIW 7 years and 8 months Link
Concentration area Type Obligatoriness
Biochemical and Molecular Pharmacology Master's Don't Required
Biochemical and Molecular Pharmacology Doctorate Don't Required
Biomedical Gerontology Master's Don't Required
Biomedical Gerontology Doctorate Don't Required
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Medical Practice Master's Don't Required
Medical Practice Doctorate Don't Required
Nephrology Master's Don't Required
Nephrology Doctorate Don't Required
Neurosciences Master's Don't Required
Neurosciences Doctorate Don't Required
Pediatrics Master's Don't Required
Pediatrics Doctorate Don't Required
Pharmaceutical Biotechnology Professional Master's Don't Required
Surgical Practice Master's Don't Required
Surgical Practice Doctorate Don't Required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Preclinical neuropharmacology This line of research is concerned with Pre-Clinical Neuropharmacology.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Respiratory Diseases / Exhaled nitric oxide and others markers of inflammation This line of research is intended to assess the role of expired nitric oxide as an inflammation marker.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Respiratory Diseases / Smoking and smoking-related diseases This line of research will address the determining factors of success/failure in smoking cessation; it will assess the role of genetics in the experimentation, maintenance and cessation of smoking; it will test the efficacy of different therapies.
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Training and Development for Teachers in Health Sciences This line of research will enable the production of scientific and technological research and the provision of Master's and Doctoral degrees as well as the conduction of Postdoc research in the area of Health Care Education.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Mechanisms of memory consolidation This line of research will look at the role of the central histaminergic system in the basolateral amygdala and in the hippocampus in the consolidation of aversive and non-aversive memory. It will also look at the influence of the treatment relying on a histidine decarboxylase inhibitor.
Developmental neurology This line of research will deal with the ontogenesis and bioelectrogenesis of the Central Nervous System (clinical aspects and animal model), sleep studies and its disorders through the assessment of clinical and neurophysiological characteristics, thus laying the foundations for the understanding of sleep medicine in childhood, and the normal and abnormal development in early childhood.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Cholinergic versus non-cholinergic components of memory The purpose of this line of research is to determine the components of memory deficits observable in transgenic rats incapable of expressing the fast transporter of hippocampal acetylcholine in different degrees. This can be applied to the treatment of the Alzheimer's disease with pro-collinergic drugs among others.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Synaptic tagging of extinction The generation of weak LTP in a dendrite of pyramidal cells of the hippocampus can increase its potential by the LTP produced in another distant dendrite. This is called synaptic tagging and is due to the tagging of the first synapsis (tag) by a local protein which attracts another generated by the second synapsis (capture).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Childhood epilepsy This line of research will address epilepsy in childhood.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
Asthma: epidemiology, genetics and the study of basic mechanisms Epidemiology of asthma in different populations.
Respiratory Failure Etiopathogenesis, epidemiology, diagnosis and management of high impact respiratory infections in the pediatric population.
Stem cells and neurodegenerative diseases To assess the possibility of recovery of central and peripheral neurological lesions resulting from neurodegenerative diseases with somatic stem cells, as well as to study the mechanisms of structural and functional recovery of lesions.
Diagnostic and Therapeutic Interventions in Newborn Infants It addresses interventions in neonatal respiratory diseases, infectious diseases and nutrition disorders.
Pediatric Clinical and Experimental Epilesy Study of epileptic syndromes that begin during childhood including etiology, pathophysiology, characterization of specific syndromes, complementary investigation, comorbidities, treatment (clinical and surgical) and evaluation / development of new antiepileptic drugs. The experimental approach uses an in vitro and in vivo model of electrophysiology and immunohistochemistry, as well as a model to verify the effects of early seizures in the developing CNS.
Clinical Epidemiology applied to child health issues Study the validity of signs, symptoms and screening and diagnostic tests; and epidemiological indicators of childhood diseases and disorders, such as incidence, prevalence and mortality, relating them to etiological and prognostic factors.
Prematurity: impact in lung development and immune response To address pulmonary growth and development, focusing on the direct and indirect effects of prematurity on the lung.
Epigenetic and Molecular Mechanisms of Developmental Stress To investigate epigenetic and molecular mechanisms related to neurocognitive and behavioral development after exposure to early stress.
Cystic Fibrosis: epidemiology, genetics and therapeutics Epidemiology, genetic diagnosis and therapy of childhood lung diseases.
Tumor Immunology To study tumor immunology
Functional evaluation and rehabilitation in chronic respiratory diseases Research in the area of ​​functional assessment and rehabilitation of patients with chronic diseases, such as cystic fibrosis and asthma. It focuses on aspects such as physical activity and physical inactivity, pulmonary function, musculoskeletal development, obesity and quality of life.
Behavioral and Developmental Neurology Study of ontogenesis and bioelectrogenesis of the Central Nervous System. It evaluates, through polysomnography, the physiological changes and gestational age dependent and the influence of neonatal neurological disorders in the process of organization of brain electrical activity. It evaluates the neurological follow-up of premature newborns, considering the effects of prematurity on neuropsychomotor development. It evaluates the follow-up of term neonates with congenital infectious pathologies and hypoxic-ischemic encephalopathy. Includes study of sleep and its disorders through the evaluation of clinical and neurophysiological characteristics forming the basis for understanding sleep medicine in childhood.
Immune responses to respiratory viral infections To analyze immune response to viral respiratory infections.
Stress and development It studies the mechanisms and development of possible therapies to prevent and / or treat the effects of early life interventions and their repercussions on the organism's development. It uses experimental research resources to study stress, inflammation, respiratory diseases, systems development, physical activity and their relationships with the life-long effects of perinatal changes.
Evaluation of the impact of interventions in early stages of development on neurochemical mechanisms and reflexes on behavior in juvenile and adult phase using animal models.
Research on the role of inflammation and the immune system in neurological diseases. Investigation of genetic and environmental factors. Development of experimental models, research on biomarkers, neurodegenerative processes, cognitive assessment and neuroimaging (magnetic resonance imaging and nuclear medicine) in diseases such as multiple sclerosis, optic neuromyelitis, anti-MOG-associated disease, acute disseminated encephalomyelitis (ADEM) and autoimmune encephalitis.
The line is designed to study all aspects related to therapy, prognosis and humanization in Pediatric Intensive Care and Emergency Units. It also includes study of aspects that refer to the professionals and management processes involved within these units.
Research and evaluation of molecular targets This line of research aims at the identification, characterization and validation of macromolecules as possible targets for the development of drugs and diagnostic tests focused on infectious, chronic degenerative, and neglected diseases. In these processes, bioinformatics tools, such as the techniques of computational molecular biophysics, will be employed. The synthesis of new chemical compounds capable of interacting with macromolecular targets will also be approached. In this line, pharmacological and toxicological studies of molecules are also developed.
Development and evaluation of biotechnology-based products This line of research involves studying the process of development of biotechnology-based products, focusing on biopharmaceuticals. Exploring the development of in vitro and in vivo diagnostic systems and their applications. Developing biological research in hypergravity, and also evaluating and characterizing nanostructured pharmaceutical materials and new radiopharmaceuticals applied in nuclear medicine.
Cell Terapy (Clinicals and experimental models, Regeneration and Tissue engineering, stem cells) This line of research will look at clinical and experimental models focused on the development of stem cells therapies, nervous regeneration and the use of stem cells in surgeries.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Peripheral nerve (Clinical and experimental models, nerve regeneration, growth factors, stem cellls) Tissue Engineering (TE) is concerned with the study of new forms of tissue production to be used in reconstructive surgeries. It covers all methods and efforts made in order to create or induce the formation of tissues in a specific location.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Practice in Medical Research Software
COD Workload Description
63348-04 60 Knowing how to use computer tools is fundamental for conducting research in health. This course is intended to explore, in a practical way, important software for medical research. The focus will be on online resources, spreadsheets, graphic programs, statistical programs, word processors, and bibliographic reference management.
Professors Home time Lattes
MARCUS HERBERT JONES 20 years and 1 month Link
Concentration area Type Obligatoriness
Biochemical and Molecular Pharmacology Master's Don't Required
Biochemical and Molecular Pharmacology Doctorate Don't Required
Biomedical Gerontology Master's Don't Required
Biomedical Gerontology Doctorate Don't Required
CTBMF Master's Don't Required
CTBMF Doctorate Don't Required
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Clinical Psychology Master's Don't Required
Clinical Psychology Doctorate Don't Required
Clinical Stomatology Master's Don't Required
Clinical Stomatology Doctorate Don't Required
Dental Materials Master's Don't Required
Dental Materials Doctorate Don't Required
Dental Prosthetics Master's Don't Required
Dental Prosthetics Doctorate Don't Required
Endodontics Master's Don't Required
Endodontics Doctorate Don't Required
Human Cognition Master's Don't Required
Human Cognition Doctorate Don't Required
Medical Practice Master's Don't Required
Medical Practice Doctorate Don't Required
Nephrology Master's Don't Required
Nephrology Doctorate Don't Required
Neurosciences Master's Don't Required
Neurosciences Doctorate Don't Required
Orthodontics and Facial Orthopedics Master's Don't Required
Orthodontics and Facial Orthopedics Doctorate Don't Required
Pediatrics Master's Don't Required
Pediatrics Inter-institutional doctorate degree Don't Required
Pediatrics Doctorate Don't Required
Restorative Dentistry Master's Don't Required
Restorative Dentistry Doctorate Don't Required
Social Psychology Master's Don't Required
Social Psychology Doctorate Don't Required
Surgical Practice Master's Don't Required
Surgical Practice Doctorate Don't Required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Preclinical neuropharmacology This line of research is concerned with Pre-Clinical Neuropharmacology.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Diagnosis and applied therapies This line of research evaluates and compares complementary diagnostic methods applied to Oral and Maxillofacial Surgery (OMS). It analyzes the results of drug therapy applied to OMS. It selects the medicinal and/or surgical therapies recommended for trauma or oral and maxillofacial pathologies.
Craniofacial growth, development and deformities This line of research focuses on studies that support the diagnosis and surgical treatment of craniofacial patients with congenital or acquired deformities.
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Theories, Techniques and Interventions in Clinical Psychology The line of research Theories, Techniques and Intervention in Clinical Psychology relies on six research groups that investigate, throughout the life cycle, psychological assessment and treatment processes as well as the development and adaptation of instruments for psychological assessment. Quantitative, qualitative and mixed designs are applied and psychoanalytical or cognitive-behavioral theories are used as theoretical background.
Stomatology diagnostic methods It aims to study the diseases of the oral and maxillofacial region and their consequences through different diagnostic methods that are applicable to them, as well as the provision of deeper insights and acquisition of new methods for clinical, laboratory and imaging diagnosis.
Oral and maxillofacial diseases ¿ clinical, immunological and anatomo-pathological studies The goal is to study, through clinical and laboratory trials, the etiopathogenesis of diseases that affect the oral cavity, as well as their consequences.
Craniomandibular Disorders This line of research studies the alterations caused by occlusal disorders directly on the temporomandibular joints, and assesses, along with signs and symptoms, the most adequate means for their resolution.
Dentistry Techniques and Devices This line of research studies the different techniques and devices, fixed and removable, according to clinical situation
Etiopathogenesis and treatment of periodontal and periapical diseases To better understand the modulatory processes involved in the onset and progression of inflammatory alterations involved in pulpal, periapical and periodontal lesions, correlating them with systemic outcomes.
Applied and Basic Cognitive Processes Esta línea de investigación se dedica al estudio básico y aplicado de la cognición humana. La principal teoría de apoyo es la Psicología Cognitiva amparada por los presupuestos del método experimental.
Psychobiology, Neuropsychology and Behavior This line of research focuses on studying the relationship between the psychobiological and neurocognitive mechanisms related to behavior.
Respiratory Diseases / Exhaled nitric oxide and others markers of inflammation This line of research is intended to assess the role of expired nitric oxide as an inflammation marker.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Respiratory Diseases / Smoking and smoking-related diseases This line of research will address the determining factors of success/failure in smoking cessation; it will assess the role of genetics in the experimentation, maintenance and cessation of smoking; it will test the efficacy of different therapies.
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Training and Development for Teachers in Health Sciences This line of research will enable the production of scientific and technological research and the provision of Master's and Doctoral degrees as well as the conduction of Postdoc research in the area of Health Care Education.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Mechanisms of memory consolidation This line of research will look at the role of the central histaminergic system in the basolateral amygdala and in the hippocampus in the consolidation of aversive and non-aversive memory. It will also look at the influence of the treatment relying on a histidine decarboxylase inhibitor.
Developmental neurology This line of research will deal with the ontogenesis and bioelectrogenesis of the Central Nervous System (clinical aspects and animal model), sleep studies and its disorders through the assessment of clinical and neurophysiological characteristics, thus laying the foundations for the understanding of sleep medicine in childhood, and the normal and abnormal development in early childhood.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Cholinergic versus non-cholinergic components of memory The purpose of this line of research is to determine the components of memory deficits observable in transgenic rats incapable of expressing the fast transporter of hippocampal acetylcholine in different degrees. This can be applied to the treatment of the Alzheimer's disease with pro-collinergic drugs among others.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Synaptic tagging of extinction The generation of weak LTP in a dendrite of pyramidal cells of the hippocampus can increase its potential by the LTP produced in another distant dendrite. This is called synaptic tagging and is due to the tagging of the first synapsis (tag) by a local protein which attracts another generated by the second synapsis (capture).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Childhood epilepsy This line of research will address epilepsy in childhood.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
Growth, Development, Diagnosis and Applied Therapies This line of research will focus on studies that support the diagnosis, planning and treatment of orthodontic and facial orthopedic cases.
Orthodontic Materials and Biocompatibility This line fosters comparative studies of biocompatible dental materials with emphasis on those that are interesting to the field of orthodontics, supported by resources available from the Schools of Biosciences, Chemistry, Pharmacy and the Toxicology Institute.
Asthma: epidemiology, genetics and the study of basic mechanisms Epidemiology of asthma in different populations.
Respiratory Failure Etiopathogenesis, epidemiology, diagnosis and management of high impact respiratory infections in the pediatric population.
Stem cells and neurodegenerative diseases To assess the possibility of recovery of central and peripheral neurological lesions resulting from neurodegenerative diseases with somatic stem cells, as well as to study the mechanisms of structural and functional recovery of lesions.
Diagnostic and Therapeutic Interventions in Newborn Infants It addresses interventions in neonatal respiratory diseases, infectious diseases and nutrition disorders.
Pediatric Clinical and Experimental Epilesy Study of epileptic syndromes that begin during childhood including etiology, pathophysiology, characterization of specific syndromes, complementary investigation, comorbidities, treatment (clinical and surgical) and evaluation / development of new antiepileptic drugs. The experimental approach uses an in vitro and in vivo model of electrophysiology and immunohistochemistry, as well as a model to verify the effects of early seizures in the developing CNS.
Clinical Epidemiology applied to child health issues Study the validity of signs, symptoms and screening and diagnostic tests; and epidemiological indicators of childhood diseases and disorders, such as incidence, prevalence and mortality, relating them to etiological and prognostic factors.
Prematurity: impact in lung development and immune response To address pulmonary growth and development, focusing on the direct and indirect effects of prematurity on the lung.
Epigenetic and Molecular Mechanisms of Developmental Stress To investigate epigenetic and molecular mechanisms related to neurocognitive and behavioral development after exposure to early stress.
Cystic Fibrosis: epidemiology, genetics and therapeutics Epidemiology, genetic diagnosis and therapy of childhood lung diseases.
Tumor Immunology To study tumor immunology
Functional evaluation and rehabilitation in chronic respiratory diseases Research in the area of ​​functional assessment and rehabilitation of patients with chronic diseases, such as cystic fibrosis and asthma. It focuses on aspects such as physical activity and physical inactivity, pulmonary function, musculoskeletal development, obesity and quality of life.
Behavioral and Developmental Neurology Study of ontogenesis and bioelectrogenesis of the Central Nervous System. It evaluates, through polysomnography, the physiological changes and gestational age dependent and the influence of neonatal neurological disorders in the process of organization of brain electrical activity. It evaluates the neurological follow-up of premature newborns, considering the effects of prematurity on neuropsychomotor development. It evaluates the follow-up of term neonates with congenital infectious pathologies and hypoxic-ischemic encephalopathy. Includes study of sleep and its disorders through the evaluation of clinical and neurophysiological characteristics forming the basis for understanding sleep medicine in childhood.
Immune responses to respiratory viral infections To analyze immune response to viral respiratory infections.
Stress and development It studies the mechanisms and development of possible therapies to prevent and / or treat the effects of early life interventions and their repercussions on the organism's development. It uses experimental research resources to study stress, inflammation, respiratory diseases, systems development, physical activity and their relationships with the life-long effects of perinatal changes.
Evaluation of the impact of interventions in early stages of development on neurochemical mechanisms and reflexes on behavior in juvenile and adult phase using animal models.
Research on the role of inflammation and the immune system in neurological diseases. Investigation of genetic and environmental factors. Development of experimental models, research on biomarkers, neurodegenerative processes, cognitive assessment and neuroimaging (magnetic resonance imaging and nuclear medicine) in diseases such as multiple sclerosis, optic neuromyelitis, anti-MOG-associated disease, acute disseminated encephalomyelitis (ADEM) and autoimmune encephalitis.
The line is designed to study all aspects related to therapy, prognosis and humanization in Pediatric Intensive Care and Emergency Units. It also includes study of aspects that refer to the professionals and management processes involved within these units.
Adhesive systems Mechanical tests of the bond strength of adhesive systems applied on dental surfaces and dental materials such as composite resin, ceramics and fiberglass. In situ and in vivo studies for testing the adhesive systems.
Restorative technologies and techniques The objective is to develop studies in laser, finite elements, mechanical tests of restorative materials applied in cavity preparation and the investigation of the potential of new technologies that can be incorporated to these techniques.
Social Psychology and Health: Individuals, Groups and Institutions The research groups in this line of research aim to study and conduct research on the psychosocial dimensions of health, the group processes and organizations and the institutional relationship between subjects, groups and institutions aiming to shed light on the processes of health/sickness in different social contexts. The theoretical-methodological approaches are primarily based on Cognitive Social Psychology, Complex Social and Systemic Epidemiology.
Psychosocial Processes: Identities, Practices and Contexts The research groups in this line aim to produce investigation focused on studying the psychosocial processes, from a sociohistorical perspective. Issues related to contemporary identity markers that connect to time, space and imaginary are addressed. The focus of interest lies in the different possibilities of expression/meaning of culture in day-to-day life, associated with the creation of perspectives for comprehension and analysis.
Cell Terapy (Clinicals and experimental models, Regeneration and Tissue engineering, stem cells) This line of research will look at clinical and experimental models focused on the development of stem cells therapies, nervous regeneration and the use of stem cells in surgeries.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Peripheral nerve (Clinical and experimental models, nerve regeneration, growth factors, stem cellls) Tissue Engineering (TE) is concerned with the study of new forms of tissue production to be used in reconstructive surgeries. It covers all methods and efforts made in order to create or induce the formation of tissues in a specific location.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Principles of Molecular Biology
COD Workload Description
63416-02 30 This course is intended to introduce students to the main theoretical and practical concepts of the area of molecular biology, applied to the health area, focusing on the main current scientific topics of molecular biology therapies.
Professors Home time Lattes
ANA PAULA DUARTE DE SOUZA 6 years and 8 months Link
Concentration area Type Obligatoriness
Biochemical and Molecular Pharmacology Master's Don't Required
Biochemical and Molecular Pharmacology Doctorate Don't Required
Biomedical Gerontology Master's Don't Required
Biomedical Gerontology Doctorate Don't Required
CTBMF Master's Don't Required
CTBMF Doctorate Don't Required
Cellular and Molecular Biology Master's Don't Required
Clinical Psychology Master's Don't Required
Clinical Psychology Doctorate Don't Required
Clinical Stomatology Master's Don't Required
Clinical Stomatology Doctorate Don't Required
Dental Materials Master's Don't Required
Dental Materials Doctorate Don't Required
Dental Prosthetics Master's Don't Required
Dental Prosthetics Doctorate Don't Required
Endodontics Master's Don't Required
Endodontics Doctorate Don't Required
Human Cognition Master's Don't Required
Human Cognition Doctorate Don't Required
Medical Practice Master's Don't Required
Medical Practice Doctorate Don't Required
Nephrology Master's Don't Required
Nephrology Doctorate Don't Required
Neurosciences Master's Don't Required
Neurosciences Doctorate Don't Required
Orthodontics and Facial Orthopedics Master's Don't Required
Orthodontics and Facial Orthopedics Doctorate Don't Required
Pediatrics Master's Don't Required
Pediatrics Doctorate Don't Required
Restorative Dentistry Master's Don't Required
Restorative Dentistry Doctorate Don't Required
Social Psychology Master's Don't Required
Social Psychology Doctorate Don't Required
Surgical Practice Master's Don't Required
Surgical Practice Doctorate Don't Required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Preclinical neuropharmacology This line of research is concerned with Pre-Clinical Neuropharmacology.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Diagnosis and applied therapies This line of research evaluates and compares complementary diagnostic methods applied to Oral and Maxillofacial Surgery (OMS). It analyzes the results of drug therapy applied to OMS. It selects the medicinal and/or surgical therapies recommended for trauma or oral and maxillofacial pathologies.
Craniofacial growth, development and deformities This line of research focuses on studies that support the diagnosis and surgical treatment of craniofacial patients with congenital or acquired deformities.
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Theories, Techniques and Interventions in Clinical Psychology The line of research Theories, Techniques and Intervention in Clinical Psychology relies on six research groups that investigate, throughout the life cycle, psychological assessment and treatment processes as well as the development and adaptation of instruments for psychological assessment. Quantitative, qualitative and mixed designs are applied and psychoanalytical or cognitive-behavioral theories are used as theoretical background.
Stomatology diagnostic methods It aims to study the diseases of the oral and maxillofacial region and their consequences through different diagnostic methods that are applicable to them, as well as the provision of deeper insights and acquisition of new methods for clinical, laboratory and imaging diagnosis.
Oral and maxillofacial diseases ¿ clinical, immunological and anatomo-pathological studies The goal is to study, through clinical and laboratory trials, the etiopathogenesis of diseases that affect the oral cavity, as well as their consequences.
Craniomandibular Disorders This line of research studies the alterations caused by occlusal disorders directly on the temporomandibular joints, and assesses, along with signs and symptoms, the most adequate means for their resolution.
Dentistry Techniques and Devices This line of research studies the different techniques and devices, fixed and removable, according to clinical situation
Etiopathogenesis and treatment of periodontal and periapical diseases To better understand the modulatory processes involved in the onset and progression of inflammatory alterations involved in pulpal, periapical and periodontal lesions, correlating them with systemic outcomes.
Applied and Basic Cognitive Processes Esta línea de investigación se dedica al estudio básico y aplicado de la cognición humana. La principal teoría de apoyo es la Psicología Cognitiva amparada por los presupuestos del método experimental.
Psychobiology, Neuropsychology and Behavior This line of research focuses on studying the relationship between the psychobiological and neurocognitive mechanisms related to behavior.
Respiratory Diseases / Exhaled nitric oxide and others markers of inflammation This line of research is intended to assess the role of expired nitric oxide as an inflammation marker.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Respiratory Diseases / Smoking and smoking-related diseases This line of research will address the determining factors of success/failure in smoking cessation; it will assess the role of genetics in the experimentation, maintenance and cessation of smoking; it will test the efficacy of different therapies.
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Training and Development for Teachers in Health Sciences This line of research will enable the production of scientific and technological research and the provision of Master's and Doctoral degrees as well as the conduction of Postdoc research in the area of Health Care Education.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Mechanisms of memory consolidation This line of research will look at the role of the central histaminergic system in the basolateral amygdala and in the hippocampus in the consolidation of aversive and non-aversive memory. It will also look at the influence of the treatment relying on a histidine decarboxylase inhibitor.
Developmental neurology This line of research will deal with the ontogenesis and bioelectrogenesis of the Central Nervous System (clinical aspects and animal model), sleep studies and its disorders through the assessment of clinical and neurophysiological characteristics, thus laying the foundations for the understanding of sleep medicine in childhood, and the normal and abnormal development in early childhood.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Cholinergic versus non-cholinergic components of memory The purpose of this line of research is to determine the components of memory deficits observable in transgenic rats incapable of expressing the fast transporter of hippocampal acetylcholine in different degrees. This can be applied to the treatment of the Alzheimer's disease with pro-collinergic drugs among others.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Synaptic tagging of extinction The generation of weak LTP in a dendrite of pyramidal cells of the hippocampus can increase its potential by the LTP produced in another distant dendrite. This is called synaptic tagging and is due to the tagging of the first synapsis (tag) by a local protein which attracts another generated by the second synapsis (capture).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Childhood epilepsy This line of research will address epilepsy in childhood.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
Growth, Development, Diagnosis and Applied Therapies This line of research will focus on studies that support the diagnosis, planning and treatment of orthodontic and facial orthopedic cases.
Orthodontic Materials and Biocompatibility This line fosters comparative studies of biocompatible dental materials with emphasis on those that are interesting to the field of orthodontics, supported by resources available from the Schools of Biosciences, Chemistry, Pharmacy and the Toxicology Institute.
Asthma: epidemiology, genetics and the study of basic mechanisms Epidemiology of asthma in different populations.
Respiratory Failure Etiopathogenesis, epidemiology, diagnosis and management of high impact respiratory infections in the pediatric population.
Stem cells and neurodegenerative diseases To assess the possibility of recovery of central and peripheral neurological lesions resulting from neurodegenerative diseases with somatic stem cells, as well as to study the mechanisms of structural and functional recovery of lesions.
Diagnostic and Therapeutic Interventions in Newborn Infants It addresses interventions in neonatal respiratory diseases, infectious diseases and nutrition disorders.
Pediatric Clinical and Experimental Epilesy Study of epileptic syndromes that begin during childhood including etiology, pathophysiology, characterization of specific syndromes, complementary investigation, comorbidities, treatment (clinical and surgical) and evaluation / development of new antiepileptic drugs. The experimental approach uses an in vitro and in vivo model of electrophysiology and immunohistochemistry, as well as a model to verify the effects of early seizures in the developing CNS.
Clinical Epidemiology applied to child health issues Study the validity of signs, symptoms and screening and diagnostic tests; and epidemiological indicators of childhood diseases and disorders, such as incidence, prevalence and mortality, relating them to etiological and prognostic factors.
Prematurity: impact in lung development and immune response To address pulmonary growth and development, focusing on the direct and indirect effects of prematurity on the lung.
Epigenetic and Molecular Mechanisms of Developmental Stress To investigate epigenetic and molecular mechanisms related to neurocognitive and behavioral development after exposure to early stress.
Cystic Fibrosis: epidemiology, genetics and therapeutics Epidemiology, genetic diagnosis and therapy of childhood lung diseases.
Tumor Immunology To study tumor immunology
Functional evaluation and rehabilitation in chronic respiratory diseases Research in the area of ​​functional assessment and rehabilitation of patients with chronic diseases, such as cystic fibrosis and asthma. It focuses on aspects such as physical activity and physical inactivity, pulmonary function, musculoskeletal development, obesity and quality of life.
Behavioral and Developmental Neurology Study of ontogenesis and bioelectrogenesis of the Central Nervous System. It evaluates, through polysomnography, the physiological changes and gestational age dependent and the influence of neonatal neurological disorders in the process of organization of brain electrical activity. It evaluates the neurological follow-up of premature newborns, considering the effects of prematurity on neuropsychomotor development. It evaluates the follow-up of term neonates with congenital infectious pathologies and hypoxic-ischemic encephalopathy. Includes study of sleep and its disorders through the evaluation of clinical and neurophysiological characteristics forming the basis for understanding sleep medicine in childhood.
Immune responses to respiratory viral infections To analyze immune response to viral respiratory infections.
Stress and development It studies the mechanisms and development of possible therapies to prevent and / or treat the effects of early life interventions and their repercussions on the organism's development. It uses experimental research resources to study stress, inflammation, respiratory diseases, systems development, physical activity and their relationships with the life-long effects of perinatal changes.
Evaluation of the impact of interventions in early stages of development on neurochemical mechanisms and reflexes on behavior in juvenile and adult phase using animal models.
Research on the role of inflammation and the immune system in neurological diseases. Investigation of genetic and environmental factors. Development of experimental models, research on biomarkers, neurodegenerative processes, cognitive assessment and neuroimaging (magnetic resonance imaging and nuclear medicine) in diseases such as multiple sclerosis, optic neuromyelitis, anti-MOG-associated disease, acute disseminated encephalomyelitis (ADEM) and autoimmune encephalitis.
The line is designed to study all aspects related to therapy, prognosis and humanization in Pediatric Intensive Care and Emergency Units. It also includes study of aspects that refer to the professionals and management processes involved within these units.
Adhesive systems Mechanical tests of the bond strength of adhesive systems applied on dental surfaces and dental materials such as composite resin, ceramics and fiberglass. In situ and in vivo studies for testing the adhesive systems.
Restorative technologies and techniques The objective is to develop studies in laser, finite elements, mechanical tests of restorative materials applied in cavity preparation and the investigation of the potential of new technologies that can be incorporated to these techniques.
Social Psychology and Health: Individuals, Groups and Institutions The research groups in this line of research aim to study and conduct research on the psychosocial dimensions of health, the group processes and organizations and the institutional relationship between subjects, groups and institutions aiming to shed light on the processes of health/sickness in different social contexts. The theoretical-methodological approaches are primarily based on Cognitive Social Psychology, Complex Social and Systemic Epidemiology.
Psychosocial Processes: Identities, Practices and Contexts The research groups in this line aim to produce investigation focused on studying the psychosocial processes, from a sociohistorical perspective. Issues related to contemporary identity markers that connect to time, space and imaginary are addressed. The focus of interest lies in the different possibilities of expression/meaning of culture in day-to-day life, associated with the creation of perspectives for comprehension and analysis.
Cell Terapy (Clinicals and experimental models, Regeneration and Tissue engineering, stem cells) This line of research will look at clinical and experimental models focused on the development of stem cells therapies, nervous regeneration and the use of stem cells in surgeries.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Peripheral nerve (Clinical and experimental models, nerve regeneration, growth factors, stem cellls) Tissue Engineering (TE) is concerned with the study of new forms of tissue production to be used in reconstructive surgeries. It covers all methods and efforts made in order to create or induce the formation of tissues in a specific location.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
QUANTITATIVE ANALYSIS IN MICROSCOPY
COD Workload Description
73195-02 30 This course is intended to enable students to understand and apply sample preparation techniques and quantitative analysis in microscopy for the different areas of biological and biomedical sciences.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
SCIENTIFIC WRITING AND COMMUNICATION
COD Workload Description
73177-04 60 This course will cover the following topics: Scientific writing in English. Structure, language and strategies for production of scientific papers. The process of paper submission and response to reviewers. Techniques for oral presentation of scientific papers in English.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
STRUCTURAL BIOLOGY
COD Workload Description
73128-02 30 This course is intended to train students in order to understand the structure of proteins and molecular modeling by the following means: crystallization of biological macromolecules, x-rays, x-ray diffraction data collection and processing, methods for determination of protein structures, crystallographic refining of biological macromolecules, analysis and interpretation of protein structures, homology modeling, relational database of protein structures. It will also lead to a discussion of projects of post-genomic studies.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
STUDY OF PROTEIN-LIGAND INTERACTIONS
COD Workload Description
13157-02 30 To follow are the topics this course will address: The determination of protein-ligand interactions. Types of interactions. Analytical methods for supramolecular studies. Quantitative methods of bond energies.
Professors Home time Lattes
PABLO MACHADO 7 years and 8 months Link
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Scientific Research Dynamics and Policies
COD Workload Description
7311B-02 30 This course intends to foster discussions on research policies in Brazil, including the assessment criteria employed by CAPES as well as scientometrics criteria. It also discusses the means for obtaining funding for scientific projects with an eye to meeting the different criteria set forth in specific projects. Additionally, one of the goals of the course is to discuss the scientific career both in Brazil and overseas and the possibilities for getting into the market. The course will discuss the differences between the areas of concentration as well as regional differences and other controversial topics in science. The peer-review process will be addressed, for both projects and scientific papers submitted to indexed journals. Part of the classes will be devoted for discussions on the ethical aspects of research, including issues such as plagiarism, co-authorship, publication of negative results, among others. Students will receive specific training to properly advise final papers as well as theses and dissertations.
Professors Home time Lattes
MARIA MARTHA CAMPOS 13 years and 8 months Link
Concentration area Type Obligatoriness
Biochemical and Molecular Pharmacology Master's Don't Required
Biochemical and Molecular Pharmacology Doctorate Don't Required
Biomedical Gerontology Master's Don't Required
Biomedical Gerontology Doctorate Don't Required
CTBMF Master's Don't Required
CTBMF Doctorate Don't Required
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Clinical Psychology Master's Don't Required
Clinical Psychology Doctorate Don't Required
Clinical Stomatology Master's Don't Required
Clinical Stomatology Doctorate Don't Required
Dental Materials Master's Don't Required
Dental Materials Doctorate Don't Required
Dental Prosthetics Master's Don't Required
Dental Prosthetics Doctorate Don't Required
Endodontics Master's Don't Required
Endodontics Doctorate Don't Required
Human Cognition Master's Don't Required
Human Cognition Doctorate Don't Required
Medical Practice Master's Don't Required
Medical Practice Doctorate Don't Required
Nephrology Master's Don't Required
Nephrology Doctorate Don't Required
Neurosciences Master's Don't Required
Neurosciences Doctorate Don't Required
Orthodontics and Facial Orthopedics Master's Don't Required
Orthodontics and Facial Orthopedics Doctorate Don't Required
Pediatrics Master's Don't Required
Pediatrics Doctorate Don't Required
Restorative Dentistry Master's Don't Required
Restorative Dentistry Doctorate Don't Required
Social Psychology Master's Don't Required
Social Psychology Doctorate Don't Required
Surgical Practice Master's Don't Required
Surgical Practice Doctorate Don't Required
Zoology Master's Don't Required
Zoology Doctorate Don't Required
Research line Description
Evaluation of mechanisms involved in inflammatory and nociceptive alterations This line of research is concerned with the evaluation of mechanisms involved in inflammatory and nociceptive alterations
Drug Development This line of research has been designed for the development of drugs against neglected tropical diseases (tuberculosis and malaria) and the development of drugs against chronic and degenerative diseases.
Preclinical neuropharmacology This line of research is concerned with Pre-Clinical Neuropharmacology.
Evaluation of pharmacological targets in cancer treatment This line of research is concerned with the evaluation of pharmacological targets in cancer treatment.
Analysis and evaluation of neurochemical and pharmacological mechanisms in neurological diseases Study of the neurochemical roots and pharmacological targets in neurological diseases.
Biological Aspects of Aging This line of research is intended for the study of basic biological characteristics that play a role in the process of aging at the molecular, cellular, biochemical, genetic and evolutionary levels, as well as their forms of interaction with environmental factors in animal models and human beings (in vitro and in vivo).
Clinical and Emotional Aspects of Aging This line is geared towards the clinical and epidemiological study of the elderly and aging. Some of the most commonly researched topics are: geriatric syndromes (cognitive impairment, postural instability, immobility, fecal incontinence, iatrogenesis, communication disorder), frailty syndrome, brain aging, mental health, osteomuscular aging, cardiometabolic risk factors and nutrition.
Social-cultural, Demographic and Bioethical Aspects of Aging This line is geared towards the study of social, cultural, economic, demographic and bioethical aspects involved in the process of aging.
Aging and Public Health This line of research is intended to study the conditions of life, health and health care received and provided to the elderly, including long-living patients. It is intended to assess primary and secondary health care services, to design of instruments for monitoring access, service routines and care provided to the elderly and long-living patients in the public health care network. Additionally, it will investigate the natural history of diseases and health conditions as well as health prevention and control, in view of the socio-demographic variables, health indicators, life styles, functional capacity, psycho-social competences and quality of life.
Diagnosis and applied therapies This line of research evaluates and compares complementary diagnostic methods applied to Oral and Maxillofacial Surgery (OMS). It analyzes the results of drug therapy applied to OMS. It selects the medicinal and/or surgical therapies recommended for trauma or oral and maxillofacial pathologies.
Craniofacial growth, development and deformities This line of research focuses on studies that support the diagnosis and surgical treatment of craniofacial patients with congenital or acquired deformities.
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.
Theories, Techniques and Interventions in Clinical Psychology The line of research Theories, Techniques and Intervention in Clinical Psychology relies on six research groups that investigate, throughout the life cycle, psychological assessment and treatment processes as well as the development and adaptation of instruments for psychological assessment. Quantitative, qualitative and mixed designs are applied and psychoanalytical or cognitive-behavioral theories are used as theoretical background.
Stomatology diagnostic methods It aims to study the diseases of the oral and maxillofacial region and their consequences through different diagnostic methods that are applicable to them, as well as the provision of deeper insights and acquisition of new methods for clinical, laboratory and imaging diagnosis.
Oral and maxillofacial diseases ¿ clinical, immunological and anatomo-pathological studies The goal is to study, through clinical and laboratory trials, the etiopathogenesis of diseases that affect the oral cavity, as well as their consequences.
Craniomandibular Disorders This line of research studies the alterations caused by occlusal disorders directly on the temporomandibular joints, and assesses, along with signs and symptoms, the most adequate means for their resolution.
Dentistry Techniques and Devices This line of research studies the different techniques and devices, fixed and removable, according to clinical situation
Etiopathogenesis and treatment of periodontal and periapical diseases To better understand the modulatory processes involved in the onset and progression of inflammatory alterations involved in pulpal, periapical and periodontal lesions, correlating them with systemic outcomes.
Applied and Basic Cognitive Processes Esta línea de investigación se dedica al estudio básico y aplicado de la cognición humana. La principal teoría de apoyo es la Psicología Cognitiva amparada por los presupuestos del método experimental.
Psychobiology, Neuropsychology and Behavior This line of research focuses on studying the relationship between the psychobiological and neurocognitive mechanisms related to behavior.
Respiratory Diseases / Exhaled nitric oxide and others markers of inflammation This line of research is intended to assess the role of expired nitric oxide as an inflammation marker.
Molecular Biology, immunology and stem cell This line of research is concerned with the study of molecular alterations in tumors, mainly those affecting the digestive and respiratory systems, through PCR techniques in real time, immunohistochemistry, flow cytometry and cell cultivation. It will also look at Cell Therapy and Tissue Engineering.
Cardiology/Risk Factors and genetics factors in cardiovascular diseases This line of research is concerned with assessing risk factors for cardiovascular surgeries using markers; traditional risk factors (dyslipidemias, arterial hypertension, diabetes, smoke addiction) and potential emerging ones (apolipoprotein B,small and dense LDL cholesterol) in coronary heart diseases.
Cardiology/Cellular therapy This line of research is intended to assess the efficiency and safety of autologous implants of bone marrow stem cells in patients suffering from dilated cardiomyopathy and in patients suffering from acute myocardial infarction.
Respiratory Diseases / Smoking and smoking-related diseases This line of research will address the determining factors of success/failure in smoking cessation; it will assess the role of genetics in the experimentation, maintenance and cessation of smoking; it will test the efficacy of different therapies.
Study abdomen adult and elderly healthy and sick with new technologies in Diagnostic Imaging First of all, this line of research is intended to introduce students to different abdominal organs in advanced imaging modalities, such as magnetic resonance and positron emission tomography. It is intended to study the normal anatomy of these organs and tissues and their anatomic variations, thus allowing for a comparison between healthy and unhealthy individuals. With this, we intent to provide deeper insights into the abdomen's normal anatomy and its anatomic variation through new imaging technologies. Additionally, this line of research will determine the diagnostic imaging accuracy of gastrointestinal tract and urinary system diseases. We are intent on reaching an earlier and more precise diagnosis of the diseases of adult and elderly patients, thus increasing their survival. It has been designed to produce researchers and professors who want to work within this line of research responsible for studying the most common diseases in our population.
Clinical Epidemiology This area of concentration is intended to develop research in clinical epidemiology focusing on its methodological and clinical aspects. This line of research intends to encourage the development of research projects that contribute to the progress in identification, intervention and promotion of determinants of the health-disease process in human population.
Functional and Molecular Image of the Body Functional imaging is the state-of-the-art in diagnostic imaging. Magnetic Resonance made a giant leap in that direction through the employment of ultra-rapid acquisition techniques, which have enabled the measurement of variations in oxygen consumption levels arising from the BOLD effect and an estimation of the cellularity of tissues through the diffusion technique. PET has enabled Nuclear Medicine to measure the level of consumption of glucose in the tissue, by making use of ionizing radiation. It is largely employed in the investigation of tumors and metastasis, which have naturally increased the consumption of glucose due to a larger metabolic level. More recently, the Dynamic PET has enabled the assessment of the consumption of glucose over time and the measurement of the most active regions more precisely.
Epidemiology and Environmental Health This course is intended to encourage the development of research into the area of epidemiology and environmental health with an eye to the methodological and clinical aspects. This line of research seeks to encourage the development of research projects that contribute to the advancement of the identification, intervention and promotion of the determinants of the health-disease process in human population.
Training and Development for Teachers in Health Sciences This line of research will enable the production of scientific and technological research and the provision of Master's and Doctoral degrees as well as the conduction of Postdoc research in the area of Health Care Education.
Extra-renal dialysis and transplatation This line of research is intended for the study of different modalities of renal replacement therapies, with emphasis on organ transplantation, especially when it comes to immunology of transplants.
Clinical nephrology and arterial hypertension This line of research will address topics related to several aspects of clinical nephrology, renal function, arterial hypertension, renal and metabolic diseases.
Cellular metabolism and membrane transport in renal and metabolic diseases (or disease states) This line of research is designed for the study of physiopathogenic mechanisms of several renal and metabolic diseases.
Mechanisms of memory consolidation This line of research will look at the role of the central histaminergic system in the basolateral amygdala and in the hippocampus in the consolidation of aversive and non-aversive memory. It will also look at the influence of the treatment relying on a histidine decarboxylase inhibitor.
Developmental neurology This line of research will deal with the ontogenesis and bioelectrogenesis of the Central Nervous System (clinical aspects and animal model), sleep studies and its disorders through the assessment of clinical and neurophysiological characteristics, thus laying the foundations for the understanding of sleep medicine in childhood, and the normal and abnormal development in early childhood.
Neurology/ stem cells This line of research is concerned with the assessment of the possibility of regeneration of central and peripheral neurological injuries resulting from neurodegenerative diseases, with somatic stem cells, as well as with the study of the structural and functional mechanisms of regeneration from injuries.
Cholinergic versus non-cholinergic components of memory The purpose of this line of research is to determine the components of memory deficits observable in transgenic rats incapable of expressing the fast transporter of hippocampal acetylcholine in different degrees. This can be applied to the treatment of the Alzheimer's disease with pro-collinergic drugs among others.
Behavioral neurology and neuropsychiatry This line of research will look at the neurobiology of psychiatric diseases and behavioral alterations in major neurological diseases.
Cognitive brain imaging This line of research will look at the development of new techniques for the analysis of neuroimaging and studies of neural bases of superior cognitive processes (for instance, language comprehension and acquisition, executive functions, spatial reasoning).
Synaptic tagging of extinction The generation of weak LTP in a dendrite of pyramidal cells of the hippocampus can increase its potential by the LTP produced in another distant dendrite. This is called synaptic tagging and is due to the tagging of the first synapsis (tag) by a local protein which attracts another generated by the second synapsis (capture).
Neurotoxic activity of ureases and derived peptides This line of research will address the neurotoxic and pro-inflammatory activities of ureases of different organisms. It will also address the methodologies of study of neurotoxicity relying on the use of insects-models. As well as this, it will look at ureases as virulence factors for pathogenic microorganisms, especially bacteria Helicobacter pylori and Proteus mirabilis and Cryptococcu yeasts.
Neuroinflammation/Multiple Sclerosis/ neuromyelitis optica The inflammation resulting from neurological diseases may be primarily involved with the physiopathology of immunomediated diseases of the nervous system, such as multiple sclerosis, neuromyelitis optica, ADEM - acute demyelinating encephalomyelitis, Guillain-Barré syndrome, autoimmune encephalitis and some neurological complications resulting directly or indirectly from viral or bacterial infections (e.g. meningoencephalitis). In other diseases, the inflammation plays a major role, but less clear than it is in strokes and in degenerative diseases of the central nervous system. The deregulation in the immune system, be it either temporary or permanent, may lead to injuries in the brain, bone marrow and peripheral nerves that cause permanent neuronal damage with the risk of aftereffects and permanent incapacity. By relying on advanced methods in molecular biology associated with clinical and imaging assessment (magnetic resonance, nuclear medicine), we have conducted research that is intended to understand the intrinsic and extrinsic mechanisms that lead to an increase of pro-inflammatory substances such as cytokines, chemokines, the production of autoantibodies, complement system activation, proliferation / maturation of autoreactive lymphocytes T and B, microglial activation and the alteration of the blood-brain barrier. Besides, we have conducted research for the identification of specific biomarkers for each disease which may assist in the establishment of better diagnosis/prognosis and in experimental animal models for the study of physiopathology and innovative therapeutic interventions.
Childhood epilepsy This line of research will address epilepsy in childhood.
Epilepsy This line of research will cover clinical and electroencephalographic, pharmacological, neuroimaging and surgical studies in the realm of epilepsy. The direct involvement of São Lucas Hospital with the diagnosis, clinical treatment and epilepsy surgery opens interesting perspectives of investigation, seeking diagnostic refinement, new treatment options and the correlations of epileptic syndromes with structural alterations of the brain.
Growth, Development, Diagnosis and Applied Therapies This line of research will focus on studies that support the diagnosis, planning and treatment of orthodontic and facial orthopedic cases.
Orthodontic Materials and Biocompatibility This line fosters comparative studies of biocompatible dental materials with emphasis on those that are interesting to the field of orthodontics, supported by resources available from the Schools of Biosciences, Chemistry, Pharmacy and the Toxicology Institute.
Asthma: epidemiology, genetics and the study of basic mechanisms Epidemiology of asthma in different populations.
Respiratory Failure Etiopathogenesis, epidemiology, diagnosis and management of high impact respiratory infections in the pediatric population.
Stem cells and neurodegenerative diseases To assess the possibility of recovery of central and peripheral neurological lesions resulting from neurodegenerative diseases with somatic stem cells, as well as to study the mechanisms of structural and functional recovery of lesions.
Diagnostic and Therapeutic Interventions in Newborn Infants It addresses interventions in neonatal respiratory diseases, infectious diseases and nutrition disorders.
Pediatric Clinical and Experimental Epilesy Study of epileptic syndromes that begin during childhood including etiology, pathophysiology, characterization of specific syndromes, complementary investigation, comorbidities, treatment (clinical and surgical) and evaluation / development of new antiepileptic drugs. The experimental approach uses an in vitro and in vivo model of electrophysiology and immunohistochemistry, as well as a model to verify the effects of early seizures in the developing CNS.
Clinical Epidemiology applied to child health issues Study the validity of signs, symptoms and screening and diagnostic tests; and epidemiological indicators of childhood diseases and disorders, such as incidence, prevalence and mortality, relating them to etiological and prognostic factors.
Prematurity: impact in lung development and immune response To address pulmonary growth and development, focusing on the direct and indirect effects of prematurity on the lung.
Epigenetic and Molecular Mechanisms of Developmental Stress To investigate epigenetic and molecular mechanisms related to neurocognitive and behavioral development after exposure to early stress.
Cystic Fibrosis: epidemiology, genetics and therapeutics Epidemiology, genetic diagnosis and therapy of childhood lung diseases.
Tumor Immunology To study tumor immunology
Functional evaluation and rehabilitation in chronic respiratory diseases Research in the area of ​​functional assessment and rehabilitation of patients with chronic diseases, such as cystic fibrosis and asthma. It focuses on aspects such as physical activity and physical inactivity, pulmonary function, musculoskeletal development, obesity and quality of life.
Behavioral and Developmental Neurology Study of ontogenesis and bioelectrogenesis of the Central Nervous System. It evaluates, through polysomnography, the physiological changes and gestational age dependent and the influence of neonatal neurological disorders in the process of organization of brain electrical activity. It evaluates the neurological follow-up of premature newborns, considering the effects of prematurity on neuropsychomotor development. It evaluates the follow-up of term neonates with congenital infectious pathologies and hypoxic-ischemic encephalopathy. Includes study of sleep and its disorders through the evaluation of clinical and neurophysiological characteristics forming the basis for understanding sleep medicine in childhood.
Immune responses to respiratory viral infections To analyze immune response to viral respiratory infections.
Stress and development It studies the mechanisms and development of possible therapies to prevent and / or treat the effects of early life interventions and their repercussions on the organism's development. It uses experimental research resources to study stress, inflammation, respiratory diseases, systems development, physical activity and their relationships with the life-long effects of perinatal changes.
Evaluation of the impact of interventions in early stages of development on neurochemical mechanisms and reflexes on behavior in juvenile and adult phase using animal models.
Research on the role of inflammation and the immune system in neurological diseases. Investigation of genetic and environmental factors. Development of experimental models, research on biomarkers, neurodegenerative processes, cognitive assessment and neuroimaging (magnetic resonance imaging and nuclear medicine) in diseases such as multiple sclerosis, optic neuromyelitis, anti-MOG-associated disease, acute disseminated encephalomyelitis (ADEM) and autoimmune encephalitis.
The line is designed to study all aspects related to therapy, prognosis and humanization in Pediatric Intensive Care and Emergency Units. It also includes study of aspects that refer to the professionals and management processes involved within these units.
Adhesive systems Mechanical tests of the bond strength of adhesive systems applied on dental surfaces and dental materials such as composite resin, ceramics and fiberglass. In situ and in vivo studies for testing the adhesive systems.
Restorative technologies and techniques The objective is to develop studies in laser, finite elements, mechanical tests of restorative materials applied in cavity preparation and the investigation of the potential of new technologies that can be incorporated to these techniques.
Social Psychology and Health: Individuals, Groups and Institutions The research groups in this line of research aim to study and conduct research on the psychosocial dimensions of health, the group processes and organizations and the institutional relationship between subjects, groups and institutions aiming to shed light on the processes of health/sickness in different social contexts. The theoretical-methodological approaches are primarily based on Cognitive Social Psychology, Complex Social and Systemic Epidemiology.
Psychosocial Processes: Identities, Practices and Contexts The research groups in this line aim to produce investigation focused on studying the psychosocial processes, from a sociohistorical perspective. Issues related to contemporary identity markers that connect to time, space and imaginary are addressed. The focus of interest lies in the different possibilities of expression/meaning of culture in day-to-day life, associated with the creation of perspectives for comprehension and analysis.
Cell Terapy (Clinicals and experimental models, Regeneration and Tissue engineering, stem cells) This line of research will look at clinical and experimental models focused on the development of stem cells therapies, nervous regeneration and the use of stem cells in surgeries.
Obesity and Metabolic Syndrome This line is concerned with research in the area of obesity and metabolic syndrome with consequences in co-morbidities involved or related to the aforementioned pathologies.
Peripheral nerve (Clinical and experimental models, nerve regeneration, growth factors, stem cellls) Tissue Engineering (TE) is concerned with the study of new forms of tissue production to be used in reconstructive surgeries. It covers all methods and efforts made in order to create or induce the formation of tissues in a specific location.
Epidemiological, Clinicopathological, Radiological and Molecular aspects of malignant neoplasms. This area of concentration is intended to describe patients who suffer from malignant neoplasms in their different clinical stages, as well as to assess their clinical outcome by looking at the clinical, histopathological, radiological and molecular variables. Studies in this area may be accountable for addressing some issues that are still controversial among the scientific community.
Videolaparoscopic Surgery This area of concentration is intended to assess the advantages of the procedures conducted using less invasive techniques.
Ecology and Conservation This line of research includes projects related to the study of the ecological relationships of animals in the broadest sense, including autoecology, ecophysiology, behavior, parasitology, population dynamics, and conservation studies.
Systematic and Biodiversity This line of research brings together projects related to the study of biodiversity in all its comparative aspects, such as Taxonomy, Systematics (morphological and molecular), morphology and inventories, in the different taxonomic groups.
Applied Zoology This line will look at biochemical, physiological and natural history studies, among others, of organisms that have a sanitary, economic, social and/or environmental interest.
TOXICOLOGY OF MEDICATIONS
COD Workload Description
73158-02 30 The following topics will be addressed in this course: The main theoretical aspects inherent to Modern Toxicology. Dose/Response relationship. Toxicology of medications as to their classification, exposure, toxicokinetics, toxicodynamics and clinical toxicology. Intoxication versus detoxication. Toxicology in the different phases of drug development.
No offer for current semester
Concentration area Type Obligatoriness
Cellular and Molecular Biology Master's Don't Required
Cellular and Molecular Biology Doctorate Don't Required
Research line Description
Cell Structure and Metabolism To follow is a list of topics this line of research is concerned with: Characterization of plant growth-promoting rhizobacteria (PGPR) and their effects on the growth and modulation of plants' secondary metabolism. Investigation into the morphological and pathophysiological basis and treatment for several diseases, such as Parkinson's and Alzheimer's, vascular accidents, depression, PTSD, epilepsy and diabetes. Characterization of the cellular and molecular mechanisms involved in inflammation and sepsis and investigation into drugs with potential anti-inflammatory action.
Cellular and Molecular Immunology To follow is a list of topics this line of research is concerned with: Development of vaccines and immunotherapies for cancer. Study of the immunosuppressive mechanisms using heat shock proteins in autoimmune diseases and transplant rejection. Investigation of psycho-neuroendocrine determinants of premature aging and immune system in healthy elderly individuals, patients with rheumatoid arthritis and bipolar disorder. Investigation into the impacts of premature stress in cognitive functions and inflammatory markers in healthy adolescents, those with bipolar disorder, and crack and cocaine addicts.
Cellular and Molecular Characterization in Microbiology and Parasitology To follow is a list of topics this line of research is concerned with: Development of new diagnostic methods for Schistosoma mansoni and Angiostrongylus cantonensis. Identification of relevant molecules involved in the immunological recognition of the host and ectoparasites, such as Rhipicephalus microplus and others affecting cattle. Isolation, cloning and expression of cDNAs of molecules and analysis of their potential immunoprotective effect. Characterization of antimicrobial resistance, virulence and clonal relations of important human and animal pathogenic agents. Investigation of phenotypes of bacterial persistence involved in the tolerance to antimicrobial agents.
Genetics, Genomics and Bioinformatics To follow is a list of topics this line of research is concerned with: Analysis of molecular markers in complex human diseases and analysis of molecular markers for forensic purposes. Phylogeny and molecular evolution of mammals. Genetics, evolution, ecology and conservation of carnivores. Evolutionary genetics of hair color of felidae. Molecular identification of biodiversity. Evolutionary and environmental genomics.
Cellular and Molecular Neurobiology To follow is a list of topics this line of research is concerned with: Animal models (zebra fish and rodents) intended to investigate the biological bases of neuropsychiatric diseases, neurodevelopment, neurotoxicology, neuropharmacology, learning and memory. In humans: aging and neurodegeneration, cognitive impairment and its association with hormone and neurotrophin levels.
Molecular Biology in the Drug/Target Interaction To follow is a list of topics this line of research is concerned with: Control and treatment of tuberculosis (drug-resistant tuberculosis) Identification of lead compounds based on defined targets, rational development of vaccines, development and validation on new diagnostic methods of multi-drug-resistant tuberculosis and new emerging genotypes. Additionally, students will make use of computer simulations in order to analyze the protein-ligand interactions. As well as this, it will address the structural study of target proteins, analysis of protein-ligand interactions and the development of bioinformatics tools. Lastly, it will focus on a description of mechanisms involved in pain, inflammation and cancer.